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High Quality Chemicals for Virus Inactivation

As a drug manufacturer, you are required to ensure the viral safety of your biological therapeutic products.

There are a variety of methods to reduce virus, such as treatments with dry heat, steam or at pH 4. For virus inactivation in proteins, such as Factor VIII or van Willebrand factor, a solvent/detergent treatment is the method of choice to inactivate lipid-coat enveloped viruses. With other proteins, such as albumine, pasteurization is the preferred option.

Chemicals, which are used for virus inactivation, must meet the same high quality standards as other raw materials in your process. All our high quality raw materials are either manufactured or purified under GMP in consistent high purity, thus making your process reliable. They bear the EMPROVE® trademark and come with comprehensive regulatory documentation that contributes to the quality of your registration dossier. The result: making your work even faster and more cost-efficient.

Our range for solvent and detergent treatment includes:

  • 1.00002 tri-n-Butyl phosphate EMPROVE® bio Ph Eur
  • 817061 Tween® 80 (Polysorbate) EMPROVE® exp Ph Eur,JP,NF
  • 108643 Triton® X-100 EMPROVE® bio Ph Eur,NF

Protein stabilizers for pasteurization:

  • 8.17081 Sodium caprylate EMPROVE® exp Ph Eur,NF
  • 100193 Caprylic acid (Octanoic acid) Ph Eur
  • 112488 N-acetyl-DL-tryptophan EMPROVE® bio Ph Eur,BP

Reagents for low pH treatment:

  • 137000 Acetic acid (glacial) 100% EMPROVE® bio Ph Eur,BP,JP,USP,ACS
  • 100193 Caprylic acid (Octanoic acid) Ph Eur
  • 1.37012 Sodium acetate trihydrate EMPROVE® bio Ph Eur,BP,JP,USP
  • 1.37046 Sodium acetate anhydrous EMPROVE® bio USP
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