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Purospher® STAR RP-18 Endcapped HPLC Columns

Outstanding Stability for Maximum Flexibility

Merck:/Freestyle/LE-Lab-Essentials/Chromatography/LE-Chrom-Column Pillow-150x100-20140219.pngPurospher® STAR RP-18 endcapped HPLC columns are designed for universal use. They allow basic, neutral, and metal chelating compounds to be separated easily with simple mobile phases – without peak tailing! Based on high-purity silica, the columns offer best all-round retention characteristics, outstanding pH stability from pH 1.5 to 10.5 over a wide temperature range, and suitability for up to 100% aqueous mobile phases. Thanks to this combination, Purospher® STAR RP-18 endcapped HPLC columns allow high-throughput applications, and give you maximum flexibility in choosing the best chromatographic conditions for any separation.

Suitable for 100% Aqueous Mobile Phases

Standard reversed phase columns, particularly RP-18 columns, often suffer from bonded phase collapse when used with highly aqueous mobile phases. Purospher® STAR RP-18 endcapped provides stable retention with excellent peak shapes, combined with the selectivity of a classical RP-18 phase – even in 100% aqueous conditions.

Features and Benefits
  • Highest purity silica (99.999%) for excellent peak symmetry
  • High separation efficiency
  • Reproducible results from run to run and batch to batch
  • Best all-round performance according to Tanaka
  • Outstanding pH stability from pH 1.5 to 10.5
  • No phase collapse when using highly aqueous mobile phases
  • Good suitability for LC-MS applications


Surface Chemistry

Merck:/Freestyle/LE-Lab-Essentials/Chromatography/LE-Chrom-Purospher Icon RP84-480x359-20140219.pngThe polymeric surface modification of Purospher® STAR RP-18 endcapped provides a virtually perfect coverage of the surface, thus preventing silanophilic interactions.

Comparison of Purospher® STAR RP-18 endcapped with other columns

Stability at Higher Temperatures

Even at a higher temperature, the long-term stability test for efficiency and retention over 15,000 column volumes clearly demonstrates the excellent stability of Purospher® STAR RP-18 endcapped columns. The data and graphs from this endurance test show no significant changes in efficiency and retention.

Stability at higher temperatures

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