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LiChrospher® RP-8 (5 µm) HPLC Columns

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ChromolithMilliporeSigma offers a broad range of HPLC columns that are fully compliant with USP (United States Pharmacopoeia) specifications. L7 USP columns are described as octyl silane (C8), chemically linked to porous silica particles, 1.5 to 10 µm in diameter. Our high-quality L7 USP columns include: LiChrospher® RP-8 (5 µm).

Reproducible Reversed-Phase Separations

LiChrospher® RP-8 (5 µm) is a highly versatile reversed-phase HPLC column suitable for acidic, neutral and weakly basic compounds. Its optimal selectivity and performance ensure reproducible separations from batch to batch. The difference in polarities is clearly described by the selectivity pattern, enabling fast, accurate method development.

Features and Benefits

  • Classified as L7 USP column
  • HPLC of acidic, neutral and weakly basic compounds
  • Optimal column selectivity and performance
  • Reproducible results due to excellent batch-to-batch consistency
  • Faster, more accurate method development

Application Examples



Specifications of LiChrospher® RP-8 (5 µm)

Sorbent characteristics Particles of silica with octyl derivative
Particle shape Spherical
Particle size 5 μm
Pore size 100 Å (10 nm)
Pore volume 1.25 mL/g
Surface area 350 m2/g
Carbon load 12.5 % C
Coverage of the surface 4.04 μmol/m2
Efficiency 55,000 N/m
pH range 2-7.5
Shipping eluent Acetonitrile/water
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