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Description
Overview
A highly potent and selective agonist for chemokine receptor 8 (CCR8) (IC50 values are 1.8 and 2.6 µM for human and mouse receptors respectively). Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion.
Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity
Standard Handling
Storage
+15°C to +30°C
Protect from Light
Protect from light
Do not freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Documentation
References
Reference overview
Haskell, C., et al. 2006. Mol Pharmacol.69, 309.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
A highly potent and selective agonist for chemokine receptor 8 (CCR8) (IC50 values are 1.8 and 2.6 µM for human and mouse receptors respectively). Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion.
Form
White solid
CAS number
874911-96-3
Chemical formula
C₂₁H₂₈N₂O₃•2HCl
Structure formula
Purity
≥98% by TLC
Solubility
H₂O
Storage
Protect from light
+15°C to +30°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.