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504815 Salmeterol Xinafoate - CAS 94749-08-3 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms:  (±) 4-Hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]m-ethyl]-1,3-benzenedimethanol xinafoate, GR 33343X xinafoate, β₂-Adrenoceptor Agonist, Salmeterol Xinafoate

Primary Target: →₂-adrenoceptor
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504815
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
94749-08-3C₂₅H₃₇NO₄ • C₁₁H₈O₃

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      Description
      OverviewA potent and selective β2-adrenoceptor agonist (EC50 = 5.3 nM) that displays bronchodilator actions. Unlike other β2- adrenoceptor agonists, Salmeterol binds to exo-site domain of β2-AR receptors, producing a slow onset of action and prolonged activation. Clinically used for the treatment of asthma and chronic obstructive pulmonary disease(COPD).
      Catalogue Number504815
      Brand Family Calbiochem®
      Synonyms (±) 4-Hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]m-ethyl]-1,3-benzenedimethanol xinafoate, GR 33343X xinafoate, β₂-Adrenoceptor Agonist, Salmeterol Xinafoate
      References
      ReferencesRoberts, J., et al. 1999. Eur. Respir. J. 14, 275.
      Rennard, S., et al. 2001. Am. J. Respir. Crit. Care Med. 163, 1087.
      Akabane, H., et al. 2006. Allergol. Int. 55, 387.
      Product Information
      CAS number94749-08-3
      FormWhite powder
      Hill FormulaC₂₅H₃₇NO₄ • C₁₁H₈O₃
      Chemical formulaC₂₅H₃₇NO₄ • C₁₁H₈O₃
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Target→₂-adrenoceptor
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +15°C to +30°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Identification Number
      Catalog Number GTIN
      5.04815.00014055977244182

      Documentation

      Salmeterol Xinafoate - CAS 94749-08-3 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Roberts, J., et al. 1999. Eur. Respir. J. 14, 275.
      Rennard, S., et al. 2001. Am. J. Respir. Crit. Care Med. 163, 1087.
      Akabane, H., et al. 2006. Allergol. Int. 55, 387.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision06-December-2018 JSW
      Synonyms (±) 4-Hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]m-ethyl]-1,3-benzenedimethanol xinafoate, GR 33343X xinafoate, β₂-Adrenoceptor Agonist, Salmeterol Xinafoate
      DescriptionA potent and selective ?2-adrenoceptor agonist (EC50 = 5.3 nM) that displays bronchodilator actions. Unlike other ?2- adrenoceptor agonists, Salmeterol binds to exo-site domain of ?2-AR receptors, producing a slow onset of action and prolonged activation. Clinically used for the treatment of asthma and chronic obstructive pulmonary disease(COPD).
      FormWhite powder
      CAS number94749-08-3
      Chemical formulaC₂₅H₃₇NO₄ • C₁₁H₈O₃
      Structure formulaStructure formula
      Purity≥98% by HPLC
      Storage Protect from light
      +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesRoberts, J., et al. 1999. Eur. Respir. J. 14, 275.
      Rennard, S., et al. 2001. Am. J. Respir. Crit. Care Med. 163, 1087.
      Akabane, H., et al. 2006. Allergol. Int. 55, 387.