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100631 Salicylic acid

Overview

Replacement Information

Key Specifications Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
69-72-7 200-712-3 C₇H₆O₃ HOC₆H₄COOH 138.12 g/mol Ph Eur,BP,USP

Pricing & Availability

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1006311000
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      Plastic bottle 1 kg
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      1006319024
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          Double PE Sack 20 kg
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          Description
          Catalogue Number100631
          Synonyms2-Hydroxybenzoic acid
          DescriptionSalicylic acid
          References
          Product Information
          CAS number69-72-7
          EC number200-712-3
          GradePh Eur,BP,USP
          Hill FormulaC₇H₆O₃
          Chemical formulaHOC₆H₄COOH
          Molar Mass138.12 g/mol
          HS Code2918 21 00
          Structure formula ImageStructure formula Image
          Quality LevelMQ500
          Applications
          Biological Information
          Physicochemical Information
          Boiling point211 °C (1013 hPa)
          Density1.443 g/cm3 (20 °C)
          Flash point157 °C
          Ignition temperature500 °C
          Melting Point157 - 159 °C
          pH value2.4 (H₂O) (saturated solution)
          Vapor pressure<1 hPa (100 °C)
          Bulk density400 - 500 kg/m3
          Solubility2 g/l
          Dimensions
          Materials Information
          Toxicological Information
          LD 50 oralLD50 Rat 1250 - 1580 mg/kg
          LD 50 dermalLD50 Rat > 2000 mg/kg
          Safety Information according to GHS
          Hazard Pictogram(s) Hazard Pictogram(s)
          Hazard Pictogram(s)
          Hazard Pictogram(s)
          Hazard Statement(s)H302: Harmful if swallowed.
          H318: Causes serious eye damage.
          H361d: Suspected of damaging the unborn child.
          Precautionary Statement(s)P280: Wear eye protection.
          P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
          Signal WordDanger
          RTECSVO0525000
          Storage class10 - 13 Other liquids and solids
          WGKWGK 1 slightly hazardous to water
          Disposal3
          Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
          Safety Information
          Hazard Symbols Hazard SymbolsHarmful
          Categories of dangerharmful, irritant
          R PhraseR 22-41
          Harmful if swallowed.Risk of serious damage to eyes.
          S PhraseS 22-24-26-39
          Do not breathe dust.Avoid contact with skin.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear eye/face protection.
          Product Usage Statements
          Storage and Shipping Information
          StorageStore at +15°C to +25°C.
          Packaging Information
          Transport Information
          Declaration (railroad and road) ADR, RIDKein Gefahrgut
          Declaration (transport by air) IATA-DGRNo Dangerous Good
          Declaration (transport by sea) IMDG-CodeNo Dangerous Good
          Supplemental Information
          Specifications
          Assay (acidimetric; calculated on dried substance)99.5 - 100.5 %
          Assay (HPLC, calc.on dried substance)98.0 - 102.0 %
          Identitypasses test
          Appearance of solution (10 %; ethanol 96 %)passes test
          Chloride (Cl)≤ 0.0100 %
          Sulfate (SO₄)≤ 0.0200 %
          Related substances / HPLC (EP) (4-Hydroxybenzoic acid)≤ 0.1 %
          Related substances / HPLC (EP) (4-Hydroxyisophthalic acid)≤ 0.05 %
          Related substances / HPLC (EP) (Phenol)≤ 0.02 %
          Related substances / HPLC (EP) (Largest unspecified impurity)≤ 0.05 %
          Related substances / HPLC (EP) (Sum of all impurities)≤ 0.2 %
          Related substances / HPLC (USP) (4-Hydroxybenzoic acid)≤ 0.1 %
          Related substances / HPLC (USP) (4-Hydroxyisophthalic acid)≤ 0.05 %
          Related substances / HPLC (USP) (Phenol)≤ 0.02 %
          Related substances / HPLC (USP) (Largest unspecified impurity)≤ 0.05 %
          Related substances / HPLC (USP) (Sum of all impurities)≤ 0.2 %
          Residual solvents (ICH Q3C)excluded by manufacturing process
          Sulfated ash≤ 0.05 %
          Loss on drying≤ 0.5 %
          Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
          corresponds to Ph Eur, BP, USP

          Documentation

          Material Qualification Dossier

          Title

          Quality Management Dossier

          Title

          Operational Excellence Dossier

          Title

          Salicylic acid SDS

          Title

          Safety Data Sheet (SDS) 

          Salicylic acid Certificates of Analysis

          Product Number PackagingSpecificationLot Number
          1006311000 Plastic bottlePDF Specification Document
          1006319024 Double PE SackPDF Specification Document

          Certificates

          Title

          Application Notes

          Title
          Water in Ammonia, aqueous