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AG980 SOX2 Control Peptide

AG980
100 µg  
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      Overview

      Replacement Information
      Description
      Catalogue NumberAG980
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionSOX2 Control Peptide
      References
      Product Information
      PresentationLiquid.
      Applications
      Application NotesAntibody blocking (AB5603)
      Optimal working concentration must be determined by the end user.
      Biological Information
      Concentration1 mg/mL
      Entrez Gene Number
      Entrez Gene SummaryThis intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
      Gene Symbol
      • SOX2
      • ANOP3
      • MGC2413
      • MCOPS3
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P48431 # Can form ternary complexes with OCT-1 or OCT-3 but acts as a transcriptional activator of FGF-4 enhancer DNA sequences only in conjunction with OCT-3 (By similarity).
      SIZE: 317 amino acids; 34310 Da
      SUBCELLULAR LOCATION: Nucleus.
      DISEASE: SwissProt: P48431 # Defects in SOX2 are the cause of microphthalmia syndromic type 3 (MCOPS3) [MIM:206900]. MCOPS3 is characterized by the association of microphthalmia or clinical anophthalmia with anomalies such as microcephaly, short stature, hypogonadotropic hypogonadism, esophageal atresia and neurologic manifestations.
      SIMILARITY: SwissProt: P48431 ## Contains 1 HMG box DNA-binding domain.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications