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03-0059-01 SMC™ Human Interleukin 22 (IL-22)

96 well assay  
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      Key Specifications Table

      Analytes AvailableSpecies ReactivityKey Applications
      IL-22 HSingle Molecule Counting (SMC™)
      Catalogue Number03-0059-01
      Trade Name
      • SMC™
      DescriptionSMC™ Human Interleukin 22 (IL-22)
      OverviewThe SMC™ IL-22 Immunoassay Kit contains all reagents required to perform the assay. This assay takes advantage of a standard immunoassay workflow configured in a standard plate format. Assay protocols are similar to existing sandwich ELISA methods with two key differences: 1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification. 2) The SMC™ immunoassay system detects analytes using Single Molecule Counting (SMC™) technology.
      Background InformationInterleukin-22 (IL-22), also known as IL-10-related T-cell-derived inducible factor (IL-TIF), is a member of the IL-10 cytokine family. Mainly produced by activated T-cells and natural killer cells, IL-22 binds to a receptor complex with two components, CRF2-4 and IL-22R. The signaling cascade is said to up-regulate pro-inflammatory cytokines and antimicrobial peptides, and induce production of acute-phase reactants in liver and hepatoma cells. The biological function of IL-22 is associated with many inflammatory disorders, including Crohn’s disease, inflammatory bowel disease, psoriasis, rheumatoid arthritis and ulcerative colitis.Thus, IL-22 remains an attractive therapeutic target because of its pro-inflammatory properties.
      Product Information
      • IL-22 Coated Beads
      • Standard Diluent
      • IL-22 Detection Antibody
      • Assay Buffer
      • IL-22 Standard
      • SMC™ Human IL-22 Immunoassay Kit Instructions
      • 10X Wash Buffer
      • Elution Buffer B
      • Buffer D
      Precision, %
      • Low-end CV% Average: 2 - 20%
      • Low-end CV% Range: 11%
      Quality LevelMQ200
      ApplicationThe sensitivity of Single Molecule Counting (SMC™) gives the SMC™ Human IL-22 Immunoassay Kit unparalleled performance in the quantification of IL-22 in human EDTA plasma.
      Key Applications
      • Single Molecule Counting (SMC™)
      Biological Information
      Species Reactivity
      • Human
      Analytes Available
      • IL-22
      • Minimum of 10 samples spiked with acceptable recovery between 80-120%.
      Physicochemical Information
      Linearity of DilutionMinimum of 10 samples spiked and diluted (at least 3 dilutions) with acceptable recovery between 80-120%.
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size96 well assay
      Transport Information
      Supplemental Information



      Erenna SMC¿ Human IL-22 Immunoassay Kit Instructions

      SMC™ Human Interleukin 22 (IL-22)


      Safety Data Sheet (SDS) 


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      Technical Info

      96 well Template 2 Up
      96 well Template Single
      Application Note: Improved performance with conversion from ELISA to an Erenna® Immunoassay
      Singulex Erenna® single molecule counting immunoassays outperform electrochemiluminescence (ECL) methods (EMD)

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