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539142 Proteasome Substrate III, Fluorogenic - Calbiochem

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539142
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539142-5MG
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      Glass bottle 5 mg
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      Description
      OverviewFluorogenic proteasome substrate. Also acts as a substrate for calpain, chymotrypsin, and ingensin.
      Catalogue Number539142
      Brand Family Calbiochem®
      SynonymsSuc-LLVY-AMC, Chymotrypsin Substrate III, Fluorogenic
      References
      ReferencesAnderson, M., et al. 1999. Exp. Eye Res. 69, 129.
      Rock, K.L., et al. 1994. Cell 78, 761.
      Tsubuki, S., et al. 1993. Biochem. Biophys. Res. Commun. 196, 1195.
      Sasaki, T., et al. 1984. J. Biol. Chem. 259, 12489.
      Product Information
      ATP CompetitiveN
      FormWhite amorphous solid
      Hill FormulaC₄₀H₅₃N₅O₁₀
      Chemical formulaC₄₀H₅₃N₅O₁₀
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetProteasome
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableN
      Emission max.
      Excitation max.
      Peptide SequenceSuc-Leu-Leu-Val-Tyr-AMC
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Proteasome Substrate III, Fluorogenic - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Proteasome Substrate III, Fluorogenic - Calbiochem Certificates of Analysis

      TitleLot Number
      539142

      References

      Reference overview
      Anderson, M., et al. 1999. Exp. Eye Res. 69, 129.
      Rock, K.L., et al. 1994. Cell 78, 761.
      Tsubuki, S., et al. 1993. Biochem. Biophys. Res. Commun. 196, 1195.
      Sasaki, T., et al. 1984. J. Biol. Chem. 259, 12489.

      Brochure

      Title
      Proteasomes Technical Bulletin

      Citations

      Title
    • Dong, Y. et al. 2006. FASEB Journal in press,.
    • Chen, E.I., et al. 2005. FASEB Journal 19, 1123.
    • Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision04-September-2008 RFH
      SynonymsSuc-LLVY-AMC, Chymotrypsin Substrate III, Fluorogenic
      DescriptionFluorogenic proteasome substrate (excitation maximum: 380 nm; emission maximum: 460 nm). Also acts as a substrate for calpain, chymotrypsin, and ingensin.
      FormWhite amorphous solid
      Chemical formulaC₄₀H₅₃N₅O₁₀
      Peptide SequenceSuc-Leu-Leu-Val-Tyr-AMC
      Purity≥98% by HPLC
      SolubilityDMSO (50 mg/ml)
      Storage -20°C
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesAnderson, M., et al. 1999. Exp. Eye Res. 69, 129.
      Rock, K.L., et al. 1994. Cell 78, 761.
      Tsubuki, S., et al. 1993. Biochem. Biophys. Res. Commun. 196, 1195.
      Sasaki, T., et al. 1984. J. Biol. Chem. 259, 12489.
      Citation
    • Dong, Y. et al. 2006. FASEB Journal in press,.
    • Chen, E.I., et al. 2005. FASEB Journal 19, 1123.