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420413 Polymyxin B Sulfate, Sterile-Filtered Aqueous Solution, Cell Culture Tested - CAS 1405-20-5 - Calbiochem

Overview

Replacement Information

Key Specifications Table

CAS #
1405-20-5

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420413-20ML
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      Description
      OverviewAn antibiotic that inhibits phospholipid sensitive Ca2+-dependent protein kinase. Mixture of polymyxin B1 sulfate and polymyxin B2 sulfate. Binds to cell wall and makes it more permeable, causing fluid uptake. Effective against Gram-negative bacteria.
      Catalogue Number420413
      Brand Family Calbiochem®
      SynonymsAerosporin, Sterile-Filtered Aqueous Solution, Cell Culture Tested
      References
      ReferencesLucas, M., et al. 1994. Biochem. Pharmacol. 47, 667.
      Ngezahayo, A. and Kolb, H.A. 1993. Pflugers Arch. 422, 413.
      Kubo, M. and Okada, Y. 1992. J. Physiol. 456, 351.
      Strasser, R.H., et al. 1992. Circ. Res. 70, 1304.
      Hegemann, L., et al. 1991. Eur. J. Pharmacol. 207, 17.
      Inaba, H. and Finkins, J.P. 1991. Am. J. Physiol. 261, R26.
      Marra, M.N., et al. 1990. J. Immunol. 144, 662.
      Product Information
      CAS number1405-20-5
      FormClear liquid
      FormulationSupplied at 50 mg/ml in H₂O.
      Quality LevelMQ100
      Applications
      Biological Information
      Biological activity≥7500 units/mg
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSTR1150000
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Harmful
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Polymyxin B Sulfate, Sterile-Filtered Aqueous Solution, Cell Culture Tested - CAS 1405-20-5 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Polymyxin B Sulfate, Sterile-Filtered Aqueous Solution, Cell Culture Tested - CAS 1405-20-5 - Calbiochem Certificates of Analysis

      TitleLot Number
      420413

      References

      Reference overview
      Lucas, M., et al. 1994. Biochem. Pharmacol. 47, 667.
      Ngezahayo, A. and Kolb, H.A. 1993. Pflugers Arch. 422, 413.
      Kubo, M. and Okada, Y. 1992. J. Physiol. 456, 351.
      Strasser, R.H., et al. 1992. Circ. Res. 70, 1304.
      Hegemann, L., et al. 1991. Eur. J. Pharmacol. 207, 17.
      Inaba, H. and Finkins, J.P. 1991. Am. J. Physiol. 261, R26.
      Marra, M.N., et al. 1990. J. Immunol. 144, 662.

      Brochure

      Title
      Antibiotics Profiler
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision30-July-2008 RFH
      SynonymsAerosporin, Sterile-Filtered Aqueous Solution, Cell Culture Tested
      DescriptionAn antibiotic that inhibits phospholipid sensitive Ca2+-dependent protein kinase. Mixture of polymyxin B1 sulfate and polymyxin B2 sulfate. Binds to cell wall and makes it more permeable, causing fluid uptake. Effective against Gram-negative bacteria.
      FormClear liquid
      FormulationSupplied at 50 mg/ml in H₂O.
      CAS number1405-20-5
      RTECSTR1150000
      Biological activity≥7500 units/mg
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Harmful
      ReferencesLucas, M., et al. 1994. Biochem. Pharmacol. 47, 667.
      Ngezahayo, A. and Kolb, H.A. 1993. Pflugers Arch. 422, 413.
      Kubo, M. and Okada, Y. 1992. J. Physiol. 456, 351.
      Strasser, R.H., et al. 1992. Circ. Res. 70, 1304.
      Hegemann, L., et al. 1991. Eur. J. Pharmacol. 207, 17.
      Inaba, H. and Finkins, J.P. 1991. Am. J. Physiol. 261, R26.
      Marra, M.N., et al. 1990. J. Immunol. 144, 662.