524731 Phosphodiesterase 4A4, His•Tag®, Human, Recombinant, S. frugiperda

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524731
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Overview

Replacement Information

Key Specifications Table

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524731-10U
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      Plastic ampoule 10 u
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      Description
      OverviewFull-length, recombinant, human phosphodiesterase 4A4 (accession no. L20965) fused at the N-terminus to a His•Tag® sequence and expressed in S. frugiperda insect cells using a baculovirus expression system. Supplied as a partially purified, catalytically active preparation.
      Catalogue Number524731
      Brand Family Calbiochem®
      SynonymscAMP-specific phosphodiesterase 4A isoform 4, PDE4A4
      Application Data
      Phosphodiesterase 4A4 was treated with increasing concentrations of the inhibitor Rolipram (Cat. No. 557330) and activity determined. The IC50 is 1.3 µM.
      References
      ReferencesGibson, L.C.D., et al. 2006. Eur. J. Pharmacol. 538, 39.
      Xu, R.X., et al. 2000. Science 288, 1822.
      Product Information
      Activity≥0.5 units/µl
      Unit of DefinitionOne unit is defined as the amount of enzyme that will convert 1 pmole cAMP to AMP per min at 30°C, pH 7.5.
      FormLiquid
      FormulationIn 150 mM NaCl, 10 mM Tris-HCl, pH 8.3.
      Quality LevelMQ100
      Applications
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Phosphodiesterase 4A4, His•Tag®, Human, Recombinant, S. frugiperda SDS

      Title

      Safety Data Sheet (SDS) 

      Phosphodiesterase 4A4, His•Tag®, Human, Recombinant, S. frugiperda Certificates of Analysis

      TitleLot Number
      524731

      References

      Reference overview
      Gibson, L.C.D., et al. 2006. Eur. J. Pharmacol. 538, 39.
      Xu, R.X., et al. 2000. Science 288, 1822.

      Brochure

      Title
      Recombinant Active Phosphodiesterases Flyer
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision03-February-2009 JSW
      SynonymscAMP-specific phosphodiesterase 4A isoform 4, PDE4A4
      Application Data
      Phosphodiesterase 4A4 was treated with increasing concentrations of the inhibitor Rolipram (Cat. No. 557330) and activity determined. The IC50 is 1.3 µM.
      DescriptionFull-length, recombinant, human phosphodiesterase 4A4 (accession no. L20965) fused at the N-terminuse to a His•Tag® sequence and expressed in S. frugiperda insect cells using a baculovirus expression system. Supplied as a partially purified, catalytically active preparation.
      FormLiquid
      FormulationIn 150 mM NaCl, 10 mM Tris-HCl, pH 8.3.
      Activity≥0.5 units/µl
      Unit definitionOne unit is defined as the amount of enzyme that will convert 1 pmole cAMP to AMP per min at 30°C, pH 7.5.
      Storage ≤ -70°C
      Avoid freeze/thaw
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesGibson, L.C.D., et al. 2006. Eur. J. Pharmacol. 538, 39.
      Xu, R.X., et al. 2000. Science 288, 1822.