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516569 PPARβ/δ Antagonist, PT-S58 - Calbiochem

The PPARβ/δ Antagonist, PT-S58 controls the biological activity of PPARβ/δ.

PPARβ/δ Antagonist, PT-S58 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: PPARβ Antagonist II, methyl 3-(N-(4-(tert-butylamino)-2-methoxyphenyl)sulfamoyl)thiophene-2-carboxylate, PPARδ Antagonist II

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516569
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Overview

Replacement Information

Key Specifications Table

Empirical Formula
C₁₇H₂₂N₂O₅S₂

Pricing & Availability

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516569-10MG
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      		 Glass bottle 10 mg
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      Description
      OverviewA cell-permeable, diaryl sulfonamide PPARβ/δ subtype-specific pure competitive antagonist with an IC50 of 98 nM. Antagonizes ligand binding without enabling coregulator interactions. Inhibits the PPARβ/δ specific agonist-induced transcriptional activity in cell cultures.
      Catalogue Number516569
      Brand Family Calbiochem®
      SynonymsPPARβ Antagonist II, methyl 3-(N-(4-(tert-butylamino)-2-methoxyphenyl)sulfamoyl)thiophene-2-carboxylate, PPARδ Antagonist II
      References
      ReferencesNaruhn, S., et al. 2011, Mol. Pharm. 80, 828.
      Product Information
      FormDark yellow solid
      Hill FormulaC₁₇H₂₂N₂O₅S₂
      Chemical formulaC₁₇H₂₂N₂O₅S₂
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      PPARβ/δ Antagonist, PT-S58 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      PPARβ/δ Antagonist, PT-S58 - Calbiochem Certificates of Analysis

      TitleLot Number
      516569

      References

      Reference overview
      Naruhn, S., et al. 2011, Mol. Pharm. 80, 828.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision18-May-2012 JSW
      SynonymsPPARβ Antagonist II, methyl 3-(N-(4-(tert-butylamino)-2-methoxyphenyl)sulfamoyl)thiophene-2-carboxylate, PPARδ Antagonist II
      DescriptionA cell-permeable, diaryl sulfonamide PPARβ/δ subtype-specific pure competitive antagonist with an IC50 of 98 nM. Antagonizes ligand binding without enabling coregulator interactions. Inhibits the PPARβ/δ specific agonist-induced transcriptional activity in cell cultures.
      FormDark yellow solid
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₁₇H₂₂N₂O₅S₂
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (100 mg/ml; clear, amber-yellow solution)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesNaruhn, S., et al. 2011, Mol. Pharm. 80, 828.