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101736 OSTEOMOLL®

101736
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      1017362500
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          Description
          Catalogue Number101736
          DescriptionOSTEOMOLL®
          OverviewOSTEOMOLL® - Solution for rapid decalcification (with fixation) for histology, is used for human cell diagnostics and serves to decalcify (demineralize) bone tissue (e. g. punched bone-marrow specimens) and other hard materials and to soften keratinized tissue of human origin, fixing the specimens in the same process.
          Decalcification is necessary for optical microscopic examinations of hard tissue in routine histological procedures. For the decalcification of sensitive, calcium-containing tissues, such as iliac crest biopsies, OSTEOSOFT® (Cat.no. 101728) can be used. Its formulation is based on EDTA. Its pendant, OSTEOMOLL®, can be used for the decalcification of hard tissue such as teeth and bone as its formulation is based on formaldehyde and hydrochloric acid. The amount of OSTEOMOLL®needed is dependent upon on the size, type and thickness of the material. A 30 ml portion of OSTEOMOLL®, which should completely cover the material, can be used twice if the solution is still clear and not contaminated.
          The material must first be cut to a thickness of max. 5 mm and an area of ​​6 cm2 (= max. Embedding cassette size). Both solutions are color-coded, to distinguish them from each other, fixatives and solvents used in the histological laboratory. OSTEOSOFT® is color-coded yellow, OSTEOMOLL® is color-coded blue. Whereby OSTEOSOFT® preserves the antigen structures in the tissue, thus, an IHC analysis can be performed, OSTEOMOLL® will be used for tissues that are not destined for antibody analysis.
          Both decalcifiers can be used for clinical diagnostic purposes and in laboratory accreditation processes as they are certified and registered as IVD and CE product. The quantity of OSTEOMOLL® required is dependent on the size, type, and density of the respective material. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.
          References
          Product Information
          HS Code3824 99 92
          Quality LevelMQ400
          Applications
          ApplicationSolution for rapid decalcification (with fixation) for histology
          Biological Information
          Physicochemical Information
          Density1.10 g/cm3 (20 °C)
          pH value<1 (H₂O, 20 °C)
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Hazard Pictogram(s) Hazard Pictogram(s)
          Hazard Pictogram(s)
          Hazard Pictogram(s)
          Hazard Statement(s)H290: May be corrosive to metals.
          H302 + H332: Harmful if swallowed or if inhaled.
          H314: Causes severe skin burns and eye damage.
          H317: May cause an allergic skin reaction.
          H335: May cause respiratory irritation.
          H341: Suspected of causing genetic defects.
          H350: May cause cancer.
          Precautionary Statement(s)P201: Obtain special instructions before use.
          P280: Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection.
          P301 + P312: IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.
          P303 + P361 + P353: IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water.
          P304 + P340 + P310: IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor.
          P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
          Signal WordDanger
          Storage class6.1D Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
          WGKWGK 3 highly hazardous to water
          Disposal9
          Carcinogenic compounds and flammable compounds labelled "Highly toxic" or "Toxic": container F. Alkyl sulfates are carcinogenic; Take particular care to avoid inhalation and skin contact. To neutralize alkyl sulfates, add dropwise (from a dropping funnel) to concentrated ice-cool Ammonia solution (Cat.No. 105426) with vigorous stirring. Before placing in container D, check the pH with pH Universal indicator strips (Cat.No. 109535).
          Safety Information
          Categories of dangerharmful, irritant, carcinogenic, sensitizing
          Product Usage Statements
          Storage and Shipping Information
          StorageStore at +15°C to +25°C.
          Packaging Information
          Transport Information
          Declaration (railroad and road) ADR, RIDUN 1789 , 8, II
          Declaration (transport by air) IATA-DGRUN 1789 , 8, II
          Declaration (transport by sea) IMDG-CodeUN 1789 , 8, II, Segregation Group: 1 (Acids)
          Supplemental Information
          Specifications
          Performance testpasses test

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          Categories

          IVD/OEM Materials & Reagents > Microscopy > Universal Reagents > Decalcification
          IVD/OEM Materials & Reagents > Microscopy > Histology > Auxiliaries for Histology