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100399 N,N-Dimethylacetamide


Replacement Information

Key Specifications Table

CAS #EC NumberHill FormulaChemical FormulaMolar Mass
127-19-5204-826-4C₄H₉NOCH₃CON(CH₃)₂87.12 g/mol

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      Catalogue Number100399
      SynonymsAcetic acid dimethylamide, Acetyldimethylamine, DMA
      OverviewSupraSolv® solvents for headspace gas chromatography are developed particularly for the analysis of residual
      solvents in drug substances, excipients and drug products according to ICH, Ph Eur and USP - SupraSolv® headspace solvents are tested for all
      residual solvents defined by the ICH.
      Product Information
      CAS number127-19-5
      EC index number616-011-00-4
      EC number204-826-4
      Hill FormulaC₄H₉NO
      Chemical formulaCH₃CON(CH₃)₂
      Molar Mass87.12 g/mol
      HS Code2924 19 99
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      ApplicationN,N-Dimethylacetamide for headspace gas chromatography SupraSolv®. CAS 127-19-5, EC Number 204-826-4, chemical formula CH₃CON(CH₃)₂.
      Biological Information
      Physicochemical Information
      Boiling point165 - 166 °C (1013 hPa)
      Density0.94 g/cm3 (20 °C)
      Explosion limit1.7 - 11.5 %(V)
      Flash point64 °C
      Ignition temperature400 °C
      Melting Point-20 °C
      pH value4 (200 g/l, H₂O, 20 °C)
      Vapor pressure2 hPa (21.7 °C)
      Solubility>1000 g/l soluble
      Materials Information
      Toxicological Information
      LD 50 oralLD50 Rat 5830 mg/kg
      Safety Information according to GHS
      Hazard Pictogram(s) Hazard Pictogram(s)
      Hazard Pictogram(s)
      Hazard Statement(s)H312 + H332: Harmful in contact with skin or if inhaled.
      H319: Causes serious eye irritation.
      H360D: May damage the unborn child.
      Precautionary Statement(s)P202: Do not handle until all safety precautions have been read and understood.
      P280: Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection.
      P302 + P352 + P312: IF ON SKIN: Wash with plenty of water. Call a POISON CENTER/doctor if you feel unwell.
      P304 + P340 + P312: IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell.
      P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
      P308 + P313: IF exposed or concerned: Get medical advice/ attention.
      Signal WordDanger
      Storage class6.1C Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
      WGKWGK 2 obviously hazardous to water
      Carcinogenic compounds and flammable compounds labelled "Highly toxic" or "Toxic": container F. Alkyl sulfates are carcinogenic; Take particular care to avoid inhalation and skin contact. To neutralize alkyl sulfates, add dropwise (from a dropping funnel) to concentrated ice-cool Ammonia solution (Cat.No. 105426) with vigorous stirring. Before placing in container D, check the pH with pH Universal indicator strips (Cat.No. 109535).
      Safety Information
      Categories of dangerirritant, toxic for reproduction, harmful
      Product Usage Statements
      Storage and Shipping Information
      StorageStore at +2°C to +30°C.
      Packaging Information
      Transport Information
      Declaration (railroad and road) ADR, RIDKein Gefahrgut
      Declaration (transport by air) IATA-DGRNo Dangerous Good
      Declaration (transport by sea) IMDG-CodeNo Dangerous Good
      Supplemental Information
      Global Trade Item Number
      Catalog Number GTIN
      1003991000 04027269256135

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