506044 Muscimol - CAS 2763-96-4 - Calbiochem

506044
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Overview

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Key Specifications Table

Empirical FormulaCAS #
C₄H₆N₂O₂ 2763-96-4

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      Glass bottle 1 mg
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      Description
      OverviewA constituent and psychoactive ingredient of the mushroom Amanita muscariathat acts as a potent agonist of GABAA receptors (EC50 = 28 µM and 33 µM in neonatal and adult rats, respectively), with preferential efficacy and selectivity to high-affinity receptor subtypes. Shown to be permeate the blood-brain barrier. Impairs associate and memory functions.
      Catalogue Number506044
      Brand Family Calbiochem®
      SynonymsGABAA Receptor Agonist, Muscimol
      References
      ReferencesChandra, D., et al. 2010. Neuropsychopharmacology. 35, 999.
      Fischer, H., et al. 2005. J. Physiol. 564, 465.
      Ramirez, D.R., et al. 2005. Neurobiol. Learning and Memory. 84, 184.
      Product Information
      CAS number2763-96-4
      FormWhite solid
      Hill FormulaC₄H₆N₂O₂
      Chemical formulaC₄H₆N₂O₂
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetGABAA
      Purity≥99% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 28

      Very toxic if swallowed.
      S PhraseS: 46

      If swallowed, seek medical advice immediately and show this container or label.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Toxic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Muscimol - CAS 2763-96-4 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Chandra, D., et al. 2010. Neuropsychopharmacology. 35, 999.
      Fischer, H., et al. 2005. J. Physiol. 564, 465.
      Ramirez, D.R., et al. 2005. Neurobiol. Learning and Memory. 84, 184.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-September-2013 JSW
      SynonymsGABAA Receptor Agonist, Muscimol
      DescriptionA constituent and psychoactive ingredient of the mushroom Amanita muscariathat acts as a potent agonist of GABAA receptors (EC50 = 28 µM and 33 µM in neonatal and adult rats, respectively), with preferential efficacy and selectivity to high-affinity receptor subtypes. Shown to be permeate the blood-brain barrier. Impairs associate and memory functions.
      FormWhite solid
      CAS number2763-96-4
      Chemical formulaC₄H₆N₂O₂
      Structure formulaStructure formula
      Purity≥99% by HPLC
      SolubilityH₂O (100 mM)
      Storage +2°C to +8°C
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Toxic
      ReferencesChandra, D., et al. 2010. Neuropsychopharmacology. 35, 999.
      Fischer, H., et al. 2005. J. Physiol. 564, 465.
      Ramirez, D.R., et al. 2005. Neurobiol. Learning and Memory. 84, 184.