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MPC4NTR10 MultiScreen Permeability Filter Plate, 0.4 µm, non-sterile

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MPC4NTR10
10  
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      Overview

      Replacement Information
      Description
      Catalogue NumberMPC4NTR10
      Trade Name
      • MultiScreen
      DescriptionMultiScreen Permeability Filter Plate, 0.4 µm, non-sterile
      Background InformationIncreasing drug candidate predictability earlier in the discovery pipeline using non-cell-based assays can improve candidate throughput during the ADME stage. Non-cell-based permeability assays are predictive models for oral absorption of development candidates.

      MultiScreen Permeability, MultiScreen-IP, and MultiScreen Acceptor plates support artificial membrane strategies for predicting passive transport.

      Membranes have uniform pore structure and density for reliable transport:
      - Individual wells minimize candidate cross-talk
      - Compatibility with automated liquid handling systems increases throughput

      Permeability Assay:
      - The MultiScreen Permeability plate has a polycarbonate membrane, which supports a hexane/hexadecane artificial layer for permeability assays.1

      PAMPA Assay:
      - The MultiScreen-IP plate has a hydrophobic PVDF membrane, which supports a lipid bilayer for PAMPA asays.2,3

      MultiScreen Acceptor Plate:
      - The MultiScreen Acceptor plate can be used with either plate to capture passively transported compounds. Constructed of 100% PTFE, the plate can improve LC/MS results depending on the charge of the small molecules being evaluated.
      References
      Product Information
      Automation CompatibleNo
      Filter CodePCF
      Color CodeClear
      Number of Wells96
      Quality LevelMQ400
      Applications
      ApplicationThis 96-well filter plate has a Polycarbonate membrane used for Permeability studies.
      Key Applications
      • Receptor/Ligand Binding Assays
      • Sample Prep
      • Enzyme Assays with Precipitation
      • DNA Purification
      • PAMPA
      Biological Information
      SterilityNon-Sterile
      Physicochemical Information
      Pore Size0.4 µm
      Dimensions
      Volume100 µL
      Materials Information
      Chemistry
      • Polycarbonate (PC)
      Device Material
      • Styrene
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Packaging Information
      Material Size10
      Transport Information
      Supplemental Information
      Specifications