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MAIPNTR10 MultiScreen IP Filter Plate, 0.45 µm, clear, non-sterile

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MAIPNTR10
10  
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      Overview

      Replacement Information
      Description
      Catalogue NumberMAIPNTR10
      Trade Name
      • MultiScreen
      DescriptionMultiScreen IP Filter Plate, 0.45 µm, clear, non-sterile
      Background InformationIncreasing drug candidate predictability earlier in the discovery pipeline using non-cell-based assays can improve candidate throughput during the ADME stage. Non-cell-based permeability assays are predictive models for oral absorption of development candidates.

      MultiScreen Permeability, MultiScreen-IP, and MultiScreen Acceptor plates support artificial membrane strategies for predicting passive transport.

      Membranes have uniform pore structure and density for reliable transport:
      - Individual wells minimize candidate cross-talk
      - Compatibility with automated liquid handling systems increases throughput

      Permeability Assay:
      - The MultiScreen Permeability plate has a polycarbonate membrane, which supports a hexane/hexadecane artificial layer for permeability assays.1

      PAMPA Assay:
      - The MultiScreen-IP plate has a hydrophobic PVDF membrane, which supports a lipid bilayer for PAMPA asays.2,3

      MultiScreen Acceptor Plate:
      - The MultiScreen Acceptor plate can be used with either plate to capture passively transported compounds. Constructed of 100% PTFE, the plate can improve LC/MS results depending on the charge of the small molecules being evaluated.
      References
      Product Information
      Automation CompatibleNo
      Filter CodeIP
      Color CodeClear
      Number of Wells96
      Quality LevelMQ400
      Applications
      ApplicationThis clear 96 well filter plate has a Hydrophobic PVDF membrane used for PAMPA.
      Key Applications
      • PAMPA
      Biological Information
      MediaImmobilon®-P
      SterilityNon-Sterile
      Physicochemical Information
      Pore Size0.45 µm
      Dimensions
      Volume50 µL–250 µL
      Materials Information
      Chemistry
      • Hydrophobic Polyvinylidene Fluoride (PVDF)
      Device Material
      • Acrylic
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Packaging Information
      Material Size10
      Transport Information
      Supplemental Information
      Specifications