Millipore Sigma Vibrant Logo

XL-85K Multi-Species Leptin RIA

XL-85K
250 tubes  
Retrieving price...
Price could not be retrieved
Minimum Quantity is a multiple of
Maximum Quantity is
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited Availability
Limited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

       

      Contact Customer Service

      Overview

      Replacement Information

      Key Specifications Table

      Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
      Leptin H, M, RRIARadioactive 125I
      Description
      Catalogue NumberXL-85K
      DescriptionMulti-Species Leptin RIA
      Background InformationLeptin is synthesized in adipocytes as a 16 kDa molecule and the circulating level is directly proportional to the total amount of fat in the body.
      References
      Product Information
      Detection methodRadioactive 125I
      HS Code2844 40 90
      Performance
      • ED80 = 3.0 ± 0.28 ng/mL HE
      • ED50 = 8.1 ± 0.60 ng/mL HE
      • ED20 = 24.4 ± 2.0 ng/mL HE, HE = Human Equivalent
      Precision, %
      • Inter-assay: 6.5–8.7
      • Intra-assay: 2.8–3.6
      Quality LevelMQ100
      Applications
      ApplicationThis radioimmunoassay (RIA) measures & quantifies Leptin for use in Metabolism & Endocrine & Neuroscience research.
      Key Applications
      • Radioimmunoassay
      Application NotesTwo-day disequilibrium incubationat 4°C. Sample volume 100 µL serum, plasma, or tissue culture media
      Biological Information
      SpecificityHuman Leptin 100% Porcine Leptin 67% Rat Leptin 61% Mouse Leptin 73% Human Insulin Not Detectable Human Proinsulin Not Detectable Human C-Peptide Not Detectable Rat Insulin Not Detectable Glucagon Not Detectable IGF-I Not Detectable Canine Lepti
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Analytes Available
      • Leptin
      Radioactive Isotype125I-Mouse Leptin
      Accuracy
      • 83–104%
      Physicochemical Information
      Linearity of Dilution94–115%
      Standard Curve Range
      • 1–50 ng/mL (Human equivalent)
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size250 tubes
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      XL-85K 04053252661631

      Documentation

      Protocols

      Title
      Protocol: Multi-Species Leptin RIA Kit

      Multi-Species Leptin RIA SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overviewPub Med ID
      Regulation of leptin synthesis in white adipose tissue of the female fruit bat, Cynopterus sphinx: role of melatonin with or without insulin.
      A Banerjee,S Udin,A Krishna
      Experimental physiology  96  2011

      Show Abstract
      20971799 20971799
      Effects of leptin supplementation to lactating Brandt\'s voles (Lasiopodomys brandtii) on the developmental responses of their offspring to a high-fat diet.
      Liu XY, Wang DH
      Journal of comparative physiology B, Biochemical, systemic, and environmental physiology  2011

      Show Abstract
      21369727 21369727
      Feeding behavior and performance of lambs are influenced by flavor diversity.
      Villalba JJ, Bach A, Ipharraguerre IR
      J Anim Sci  2011

      Show Abstract
      21454862 21454862
      Postprandial response of plasma insulin, amylin and acylated ghrelin to various test meals in lean and obese cats.
      Martin LJ, Siliart B, Lutz TA, Biourge V, Nguyen P, Dumon HJ
      The British journal of nutrition  2010

      Show Abstract
      20100379 20100379
      Peripartal feeding strategy with different n-6:n-3 ratios in sows: effect on gene expression in backfat white adipose tissue postpartum.
      Papadopoulos GA, Erkens T, Maes DG, Peelman LJ, van Kempen TA, Buyse J, Janssens GP
      Br J Nutr  101  197-205. Epub 2008 May 23.  2009

      Show Abstract
      18498673 18498673
      Hypothalamic suppressor-of-cytokine-signalling 3 mRNA is elevated and pro-opiomelanocortin mRNA is reduced during pregnancy in Brandt's voles (Lasiopodomys brandtii ).
      G-B Tang, J-G Cui, D-H Wang
      Journal of neuroendocrinology  20  1038-44  2008

      Show Abstract
      18638026 18638026
      Molecular cloning and expression of leptin in gray and harbor seal blubber, bone marrow, and lung and its potential role in marine mammal respiratory physiology.
      John A Hammond, Kimberley A Bennett, Michael J Walton, Ailsa J Hall
      American journal of physiology. Regulatory, integrative and comparative physiology  289  R545-R553  2005

      Show Abstract
      15831765 15831765
      Comparing mRNA levels of genes encoding leptin, leptin receptor, and lipoprotein lipase between dairy and beef cattle.
      M Q Ren, J Wegner, O Bellmann, G A Brockmann, F Schneider, F Teuscher, K Ender
      Domestic animal endocrinology  23  371-81  2002

      Show Abstract
      12206871 12206871
      Plasma leptin determination in ruminants: effect of nutritional status and body fatness on plasma leptin concentration assessed by a specific RIA in sheep.
      C Delavaud, F Bocquier, Y Chilliard, D H Keisler, A Gertler, G Kann
      The Journal of endocrinology  165  519-26  2000

      Show Abstract
      10810316 10810316
      Leptin expression in offspring is programmed by nutrition in pregnancy.
      J E Eckert, K L Gatford, B G Luxford, R G Campbell, P C Owens
      The Journal of endocrinology  165  R1-6  2000

      Show Abstract
      10828858 10828858

      Brochure

      Title
      A closer look at immunoassay platforms: Beyond fit for purpose
      Custom Immunoassay Menu of Services
      ELISAs, RIAs & GyroMark HT Assays

      Technical Info

      Title
      Quality Control Range Sheet- LPG-136 and LPG-236
      Quality Control Ranges: Human Leptin ELISA (Normal & Sensitive) Kit

      Data Sheet

      Title
      Full Service Custom-built Assays

      Related Products & Applications

      Related Products

      Catalog Number Description  
      CGTMAG-98K MILLIPLEX Canine Gut Hormone Magnetic Bead Panel - Endocrine Multiplex Assay Show Pricing & Availability
      HADCYMAG-61K MILLIPLEX MAP Human Adipocyte Magnetic Bead Panel - Endocrine Multiplex Assay Show Pricing & Availability
      HADK2MAG-61K MILLIPLEX MAP Human Adipokine Magnetic Bead Panel 2 - Endocrine Multiplex Assay Show Pricing & Availability

      Categories

      Life Science Research > Antibodies and Assays > Immunoassays > Radioimmunoassay (RIA) > Complete RIA Kits
      Life Science Research > Protein Detection and Quantification > Immunoassays > Radioimmunoassay (RIA) > Complete RIA Kits