Our broad portfolio consists of multiplex panels that allow you to choose, within the panel, analytes that best meet your needs. On a separate tab you can choose the premixed cytokine format or a single plex kit.
Cell Signaling Kits & MAPmates™
Choose fixed kits that allow you to explore entire pathways or processes. Or design your own kits by choosing single plex MAPmates™, following the provided guidelines.
The following MAPmates™ should not be plexed together:
-MAPmates™ that require a different assay buffer
-Phospho-specific and total MAPmate™ pairs, e.g. total GSK3β and GSK3β (Ser 9)
-PanTyr and site-specific MAPmates™, e.g. Phospho-EGF Receptor and phospho-STAT1 (Tyr701)
-More than 1 phospho-MAPmate™ for a single target (Akt, STAT3)
-GAPDH and β-Tubulin cannot be plexed with kits or MAPmates™ containing panTyr
.
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Select A Species, Panel Type, Kit or Sample Type
To begin designing your MILLIPLEX® MAP kit select a species, a panel type or kit of interest.
Custom Premix Selecting "Custom Premix" option means that all of the beads you have chosen will be premixed in manufacturing before the kit is sent to you.
If you have chosen panel analytes and then choose a premix or single plex kit, you will lose that customization.
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96-Well Plate
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Add Additional Reagents (Buffer and Detection Kit is required for use with MAPmates)
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48-602MAG
Buffer Detection Kit for Magnetic Beads
1 Kit
Space Saver Option Customers purchasing multiple kits may choose to save storage space by eliminating the kit packaging and receiving their multiplex assay components in plastic bags for more compact storage.
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Millistak+® DE Stacked Disc Filters
Clarification/prefiltration filters specifically developed to meet the critical needs of the pharmaceutical and biotechnology industries.More
Clarification/prefiltration filters specifically developed to meet the critical needs of the pharmaceutical and biotechnology industries. Less
Impact of Design and Selection of Prefilters on Operating Cost Honig, Ephraim S., and Perry D. Schwartz; Filtration & Separation (Jan/Feb 1997). Filtration & Separation (Jan/Feb 1997).
1997
FAQ
Question
Answer
What are the flushing recommendations for prefilters?
C5939Clarification/prefiltration filters specifically developed to meet the critical needs of the pharmaceutical and biotechnology industries.
Description
Millistak+® DE stacked discs are clarification/prefiltration filters that have been specifically developed to meet the critical needs of the pharmaceutical and biotechnology industries. The Millistak+® DE filter cells consist of a broad range of controlled porosity graded density depth media housed in chemically stable polypropylene.
To meet the stringent needs of the biopharmaceutical industry, the Millistak+® DE filters undergo rigorous testing to ensure high wet tensile strength, low gravimetric extractables, and low oxidizable substances. The plastic components and materials meet USP Class VI non-toxicity requirements for pharmaceutical manufacturing.
The Millistak+® DE stacked disc filters satisfy application needs in the bio-pharmaceutical market where high concentrations of colloidal contaminants dictate the need for high surface area depth media with a positive charge.
Benefits
Monitored gradient density matrix assures consistent filtration performance
Filter matrix exhibits positive charge properties to enhance filtration performance
Broad range of media grades to assure optimal performance
Dimensions
Stack Design
Stack Height, cm (in)
16" Diameter Stack
F (6 cell)
19.4 (7.63)
N/A
J (9 cell)
19.4 (7.63)
N/A
N (13 cell)
27.6 (10.88)
N/A
R (16 cell)
27.6 (10.88)
N/A
T (16 cell)
27.6 (10.88)
3.47 m²
Materials of Construction
Filter Media
Cellulose (CL) Inorganic Filter Aid
Structural Components
Polypropylene
Maximum Differential Pressure, bar (psid)
Forward: 2.07 bar (30 psid) @ 25 °C; 1.03 bar (15 psid) @ 80 °C; 0.21 bar (3 psid) @ 123 °C. Reverse: 0.03 bar (0.5 psid)
Bacterial Endotoxins
Aqueous extraction contains <0.25 EU/mL as determined by the Limulus Amebocyte Lysate (LAL) clot test technique
Component Material Toxicity
Component materials meet the criteria of the USP <88> Reactivity Test for Class VI Plastics. These products meet the requirements of the USP <88> Safety Test, utilizing a 0.9% sodium chloride extraction.
Oxidizable Substances
The effluent of an autoclaved (1 cycle of 30 minutes @ 123 °C) stacked device is negative after a WFI flush of 5 liters per ft2 (50 L/m2) of media surface area
Extractables
Post autoclave (1 cycle of 30 minutes at 123 °C) and pure water flush of 50 L/m2 (5 L/ft2) of media surface area. NVR: 3.93–6.43 mg/m2 TOC: 753–1,567 ppb
Indirect Food Additive
All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182.
Sterilization
May be steam sterilized for 3 steam-in-place (SIP) cycles of 30 minutes @ 123 °C
Sanitization
May be hot water sanitized for 20 cycles using purified water @ 80 °C for 30 minutes
Conductivity
9-12 µS/cm after a pure water flush of 50 L/m2 (5 L/ft2) of media surface area per autoclaved (1 cycle of 30 minutes at 123 ºC) 12" 16-stack device
