FCMAB177F Milli-Mark™ Anti-CD10-FITC Antibody, clone SS2/36

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FCMAB177F
100 tests  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H FC M FITC Monoclonal Antibody
      Description
      Catalogue NumberFCMAB177F
      Trade Name
      • Milli-Mark
      DescriptionMilli-Mark™ Anti-CD10-FITC Antibody, clone SS2/36
      Alternate Names
      • Neprilysin
      • Neutral endopeptidase 24.11
      • Neutral endopeptidase (NEP)
      • Enkephalinase
      • Atriopeptidase
      • Common acute
      • ymphocytic leukemia antigen (CALLA)
      Background InformationCD10 is a 100 kDa protein belonging to a family of type II transmembrane metalloproteases which also includes the leukocyte antigens CD13, CD26, CD73 and aminopeptidase. The gene encoding CD10 is located on chromosome 3. CD10 is a zinc-dependent enzyme and is thought to down-regulate cellular responses to peptide hormones (Barclay, 1997). On lymphoid cells, CD10 is expressed on immature T and B precursor cells but is lost as the cells reach maturation. CD10 is, however, re-expressed on proliferating B cells and mature neutrophils (Jones, 1997). Anti-CD10, SS2/36, was included in the Third International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with CD 10 (Majdic, 1987).
      References
      Product Information
      FormatFITC
      Control
      • PBMCs
      PresentationPurified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
      Quality LevelMQ100
      Applications
      ApplicationMilli-Mark Anti-CD10-FITC Antibody, clone SS2/36 detects level of CD10 & has been published & validated for use in FC.
      Key Applications
      • Flow Cytometry
      Biological Information
      ImmunogenAcute lymphoblastic leukemia cells
      CloneSS2/36
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityAntibody recognizes Human CD10 antigen.
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Purification MethodProtein A Purfied
      UniProt Number
      Molecular Weight 100 kDa (Barclay, 1997)
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by flow cytometry using human PBMCs
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.
      Packaging Information
      Material Size100 tests
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Milli-Mark™ Anti-CD10-FITC Antibody, clone SS2/36 SDS

      Title

      Safety Data Sheet (SDS) 

      Milli-Mark™ Anti-CD10-FITC Antibody, clone SS2/36 Certificates of Analysis

      TitleLot Number
      Milli-Mark Anti-CD10-FITC, clone SS2/36 - NG1940533NG1940533
      Milli-Mark Anti-CD10-FITC, clone SS2/36 - NRG1761327NRG1761327
      Milli-Mark™ Anti-CD10-FITC, clone SS2/36 - 29063342906334
      Milli-Mark™ Anti-CD10-FITC, clone SS2/36 - 31833693183369
      Milli-Mark™ Anti-CD10-FITC, clone SS2/36 - 24296882429688
      Milli-Mark™ Anti-CD10-FITC, clone SS2/36 - 24532922453292
      Milli-Mark™ Anti-CD10-FITC, clone SS2/36 - 22763842276384
      Milli-Mark™ Anti-CD10-FITC, clone SS2/36 - 23701682370168

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies