444228 MMP-7 Substrate, Fluorogenic - Calbiochem

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444228
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Overview

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Key Specifications Table

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444228-1MG
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      Description
      OverviewExcellent fluorogenic substrate for MMP-7 (kcat/Km = 1.9 x 105 M-1 s-1). The cleavage occurs at the Ala-Leu bond.
      Catalogue Number444228
      Brand Family Calbiochem®
      SynonymsMatrilysin Substrate, PUMP-1 Substrate, DNP-RPLALWRS
      References
      ReferencesWelch, A.R., et al. 1996. Biochemistry 35, 10103.
      Welch, A.R., et al. 1995. Arch. Biochem. Biophys. 324, 59.
      Product Information
      ATP CompetitiveN
      FormYellow solid
      Hill FormulaC₅₂H₇₇N₁₇O₁₄
      Chemical formulaC₅₂H₇₇N₁₇O₁₄
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetFluorogenic substrate for MMP-7
      Primary Target IC<sub>50</sub>kcat/Km = 1.9 x 105 M⁻¹ s⁻¹for MMP-7
      Purity≥90% by HPLC
      Physicochemical Information
      Cell permeableN
      Emission max.
      Excitation max.
      Peptide SequenceDNP-Arg-Pro-Leu-Ala-Leu-Trp-Arg-Ser-OH
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      MMP-7 Substrate, Fluorogenic - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      MMP-7 Substrate, Fluorogenic - Calbiochem Certificates of Analysis

      TitleLot Number
      444228

      References

      Reference overview
      Welch, A.R., et al. 1996. Biochemistry 35, 10103.
      Welch, A.R., et al. 1995. Arch. Biochem. Biophys. 324, 59.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision06-August-2008 RFH
      SynonymsMatrilysin Substrate, PUMP-1 Substrate, DNP-RPLALWRS
      DescriptionExcellent fluorogenic substrate for MMP-7 (kcat/Km = 1.9 x 105 M-1s-1). Excitation maximum: ~280 nm; emission maximum: ~360 nm. The cleavage occurs at the Ala-Leu bond.
      FormYellow solid
      Chemical formulaC₅₂H₇₇N₁₇O₁₄
      Peptide SequenceDNP-Arg-Pro-Leu-Ala-Leu-Trp-Arg-Ser-OH
      Purity≥90% by HPLC
      Solubility10% Acetic acid (1 mg/ml)
      Storage -20°C
      Protect from moisture
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesWelch, A.R., et al. 1996. Biochemistry 35, 10103.
      Welch, A.R., et al. 1995. Arch. Biochem. Biophys. 324, 59.

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      Categories

      Life Science Research > Proteins and Enzymes > Substrate & Control Proteins > Protease Substrates