444244 MMP-2 Inhibitor I - CAS 10335-69-0 - Calbiochem

Overview

Replacement Information

Key Specifications Table

Empirical FormulaCAS #
C₁₈H₃₅NO₂ 10335-69-0

Pricing & Availability

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444244-10MG
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      Plastic ampoule 10 mg
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      Description
      OverviewA cell-permeable, potent inhibitor of MMP-2 that acts in a dose-dependent manner (Ki = 1.7 µM).
      Catalogue Number444244
      Brand Family Calbiochem®
      Synonymscis-9-Octadecenoyl-N-hydroxylamide, Oleoyl-N-hydroxylamide, OA-Hy
      References
      ReferencesBerton, A., et. al. 2001. J. Biol. Chem. 276, 20458.
      Emonard, H., et al. 1999. Ann. N.Y. Acad. Sci. 878, 647.
      Product Information
      CAS number10335-69-0
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₁₈H₃₅NO₂
      Chemical formulaC₁₈H₃₅NO₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetMMP-2
      Primary Target K<sub>i</sub>1.7 mM
      Purity≥98% by TLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsUnstable in solution; reconstitute just prior to use.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      MMP-2 Inhibitor I - CAS 10335-69-0 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      MMP-2 Inhibitor I - CAS 10335-69-0 - Calbiochem Certificates of Analysis

      TitleLot Number
      444244

      References

      Reference overview
      Berton, A., et. al. 2001. J. Biol. Chem. 276, 20458.
      Emonard, H., et al. 1999. Ann. N.Y. Acad. Sci. 878, 647.

      Citations

      Title
    • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
    • Michelle K.Y. Siu and C. Yan Cheng. (2004) Interactions of proteases, protease inhibitors, and the β1 integrin/laminin γ3 protein complex in the regulation of ectoplasmic specialization dynamics in the rat testis. Biology of Reproduction 70, 945-964.
    • Feng Zheng, et al. (2004) Development of albuinuria and glomerular lesions in normoglycemic B6 recepients of db/db mice bone marrow. Diabetes 53, 2420-2427.
    • Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision03-April-2008 RFH
      Synonymscis-9-Octadecenoyl-N-hydroxylamide, Oleoyl-N-hydroxylamide, OA-Hy
      DescriptionPotent inhibitor of MMP-2 (gelatinase A). Inhibits MMP-2 in a dose dependent manner (Ki = 1.7 µM)
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number10335-69-0
      Chemical formulaC₁₈H₃₅NO₂
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityDMSO (2 mg/ml) or Ethanol (3 mg/ml)
      Storage -20°C
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsUnstable in solution; reconstitute just prior to use.
      Toxicity Standard Handling
      ReferencesBerton, A., et. al. 2001. J. Biol. Chem. 276, 20458.
      Emonard, H., et al. 1999. Ann. N.Y. Acad. Sci. 878, 647.
      Citation
    • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
    • Michelle K.Y. Siu and C. Yan Cheng. (2004) Interactions of proteases, protease inhibitors, and the β1 integrin/laminin γ3 protein complex in the regulation of ectoplasmic specialization dynamics in the rat testis. Biology of Reproduction 70, 945-964.
    • Feng Zheng, et al. (2004) Development of albuinuria and glomerular lesions in normoglycemic B6 recepients of db/db mice bone marrow. Diabetes 53, 2420-2427.