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TGFBMAG-64K-01 MILLIPLEX MAP TGFß1 Magnetic Bead Single Plex Kit - Immunology Multiplex Assay

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      Replacement Information

      Key Specifications Table

      Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
      TGF-β1 H, M, R, NhP, Ca, Fe, Po Mplex Luminex xMAP
      Catalogue NumberTGFBMAG-64K-01
      Trade Name
      DescriptionMILLIPLEX MAP TGFß1 Magnetic Bead Single Plex Kit - Immunology Multiplex Assay
      Background InformationThe transforming growth factor beta (TGFβ) system, a superfamily of cytokines as well as signaling pathways, is highly conserved throughout the animal kingdom. TGFβ functions in immune cell development, angiogenesis, wound healing and embryonic development, bone development and plays a critical role in immune response, heart disease, and cancer. In its normal state TGFβ is one of the few classes of proteins able to inhibit cell growth by halting mitosis at the G1 state, inducing cell differentiation or apoptosis. However, during oncogenesis mutations in the TGFβ signaling pathway result in tumor cell resistance to the effects of normally functioning TGFβ, causing proliferation without regulation. Initial research suggests that VE-cadherin may enhance the mutated TGFβ signaling pathway.
      Product Information
      Detection methodLuminex xMAP
      ConfigurationSingle Plex
      Precision, %
      • Inter-assay: < 10
      • Intra-assay: < 10
      Panel TypeMAGNETIC Cytokines/Chemokines
      Quality LevelMQ200
      ApplicationThis MILLIPLEX MAP TGF ß1 (Transforming Growth Factor Beta) - Single Plex is an Immunology Multiplex Assay used for the simultaneous quantification of theTGF-β1 biomarker in the following species: Mouse/Human/Rat/Pig/Horse/Rabbit/Guinea Pig/Hamster.
      Key Applications
      • Multiplexing
      Application Notes• This assay requires an acidification sample treatment.
      • This is a 2-hour or overnight incubation assay.
      • This assay requires 25 μL of a 1:30 dilution after treatment of serum and plasma samples.
      Biological Information
      SpecificityIn addition to human TGFβ1, the assay can detect TGFβ1 in serum of the following; horse, rabbit, mouse, rat, mini pig, canine, hamster, guinea pig, rhesus monkey and cynomolgous monkey. However, the exact amount of cross reactivity has not been determined.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      • Non-human Primate
      • Canine
      • Feline
      • Pig
      Analytes Available
      • TGF-β1
      Assay PanelEverything you need in a single kit.
      • 100%
      Physicochemical Information
      • 12 pg/mL
      Standard Curve Range
      • 9.8 - 2,500 pg/mL
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsRecommended storage for kit components is 2 - 8°C.
      Packaging Information
      Material Size96-well plate
      Transport Information
      Supplemental Information



      Protocol: TGFβ 1,2,3 Magnetic Bead Kit

      MILLIPLEX MAP TGFß1 Magnetic Bead Single Plex Kit - Immunology Multiplex Assay SDS


      Safety Data Sheet (SDS) 


      Reference overviewPub Med ID
      Blockade of A2B adenosine receptor reduces left ventricular dysfunction and ventricular arrhythmias 1 week after myocardial infarction in the rat model.
      Zhang, H; Zhong, H; Everett, TH; Wilson, E; Chang, R; Zeng, D; Belardinelli, L; Olgin, JE
      Heart rhythm : the official journal of the Heart Rhythm Society  11  101-9  2014

      Show Abstract
      24120874 24120874
      Low-dose gemcitabine depletes regulatory T cells and improves survival in the orthotopic Panc02 model of pancreatic cancer.
      Shevchenko, I; Karakhanova, S; Soltek, S; Link, J; Bayry, J; Werner, J; Umansky, V; Bazhin, AV
      International journal of cancer. Journal international du cancer  133  98-107  2013

      Show Abstract
      23233419 23233419


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      Technical Info

      96 well Template 2 Up
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      Life Science Research > Protein Detection and Quantification > Immunoassays > Multiplexed Immunoassays > Milliplex MAP Assay Products > Premixed Kits