HDIAB-34K-PMX5 | MILLIPLEX MAP Human Diabetes Panel, Premixed 5 Plex Assay

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      Key Specifications Table

      Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
      Insulin, Glucagon, Leptin, GLP-1 (Active), C-Peptide H Mplex Luminex xMAP
      Catalogue NumberHDIAB-34K-PMX5
      Trade Name
      DescriptionMILLIPLEX MAP Human Diabetes Panel, Premixed 5 Plex Assay
      OverviewEMD Millipore’s MILLIPLEX® MAP Human Diabetes Premixed Magnetic Bead Panel is a 5-plex kit to be used for the simultaneous quantification of the following analytes in serum, plasma or culture supernatant samples: insulin, glucagon, leptin, GLP-1 (Active) and C-Peptide.

      MILLIPLEX® MAP offers the broadest selection of analytes across a wide range of disease states and species. Once the analytes of interest have been identified, you can rely on the quality that we build into each kit to produce results you can trust. In addition to the assay characteristics listed in the protocol, other performance criteria evaluated during the validation process include: cross-reactivity, dilution linearity, kit stability, and sample behavior (e.g. detectability and stability). Each panel and kit meets stringent manufacturing criteria to ensure batch-to-batch reproducibility.

      Each MILLIPLEX® MAP panel and kit includes:
      • Quality controls (QCs) provided to qualify assay performance

      • Comparison of standard (calibrator) and QC lots to a reference lot to ensure lot-to-lot consistency

      • Optimized serum matrix to mimic native analyte environment

      • Detection antibody cocktails designed to yield consistent analyte profiles within panel

      MILLIPLEX® MAP offers you:
      o The ability to choose any combination of analytes from our panel of seven analytes to design a custom kit that better meets your needs.
      o A convenient “all-in-one” box format that gives you the assurance that you will have all the necessary reagents you need to run your assay.

      EMD Millipore’s MILLIPLEX® MAP Human Diabetes Premixed Magnetic Bead Panel is part of the most versatile system available for metabolic hormone research. From our single to multiplex biomarker solutions, we partner with you to design, develop, analytically validate and build the most comprehensive library available for protein detection and quantitation.
      Background InformationType I Diabetes is an autoimmune disease (or a viral attack) that destroys pancreatic β-cells leaving the subject unable to produce insulin (usually early onset). Type II Diabetes is a metabolic disorder caused by obesity and a sedentary lifestyle (usually later onset). If the body is unable to produce sufficient levels of insulin, then Glucose levels will rise and in time, can cause heart disease, stroke, kidney failure and dementia, to name a few. The five analytes included in this kit are: insulin, glucagon, leptin, glucagon-like peptide (GLP-1 active), and C-Peptide (connecting peptide).

      The MILLIPLEX® MAP Human Diabetes Premixed Magnetic Bead Panel enables you to focus on the relevance and therapeutic potential of insulin, glucagon, leptin, GLP-1 (Active), and C-Peptide in your research model. Coupled with the Luminex xMAP® platform in a magnetic bead format, you receive the advantage of ideal speed and sensitivity, allowing quantitative multiplex detection of multiple analytes simultaneously, which can dramatically improve productivity.
      Product Information
      Detection methodLuminex xMAP
      Precision, %
      • Intra-assay: <10%
      • Inter-assay: <15% C-Peptide, Glucagon, Insulin, Leptin and <20% GLP-1 Active
      Panel TypeMAGNETIC Metabolism
      ApplicationThe analytes available for this multiplex kit are: Insulin, Glucagon, Leptin, Glucagon-like peptide (GLP-1 active) and C-Peptide.
      Key Applications
      • Multiplexing
      Application Notes• This kit is a 5-plex, premixed bead kit.
      • Two of the analytes require addition of DPPIV inhibitor (for GLP-1 active) and Aprotinin (for Glucagon). Refer to the sample collection and storage section in the protocol for details.
      • The protocol recommends samples be run neat, using an overnight incubation for optimal sensitivity.
      Biological Information
      Species Reactivity
      • Human
      Analytes Available
      • Insulin
      • Glucagon
      • Leptin
      • GLP-1 (Active)
      • C-Peptide
      Physicochemical Information
      • Glucagon 9.6 pg/mL
      • Leptin 38.5 pg/mL
      • GLP-1 (active) 1.1 pg/mL
      • Insulin 22.1 pg/mL
      • C-Peptide 8.4 pg/mL
      Standard Curve Range
      • C-Peptide: 27.4 - 20,000 pg/mL
      • GLP-1 (active): 2.7 - 2,000 pg/mL
      • Glucagon: 13.7 - 10,000 pg/mL
      • Insulin: 137 - 100,000 pg/mL
      • Leptin:137 - 100,000 pg/mL
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size96-well plate
      Transport Information
      Supplemental Information



      Human Diabetes Magnetic Bead Panel



      Safety Data Sheet (SDS) 


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