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HCVD6MAG-67K MILLIPLEX® MAP Human Cardiovascular Disease Magnetic Bead Panel 6 - Cardiovascular Disease (CVD) Multiplex Assay

The analytes available for this multiplex kit are: sCD14, DPP4/sCD26, Endostatin, pGRN, LRG1, MCAM, ucMGP

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Multiplexing Detection Methods: Luminex xMAP Research Sub-Category: Cardiovascular Disease, Metabolic Disorders Research Category: Cardiovascular Disease
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HCVD6MAG-67K
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Overview

Replacement Information

Key Specifications Table

Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
sCD14, sCD26, Endostatin, pGRN, LRG1, MCAM/sCD146, ucMGP H Mplex Luminex xMAP
Description
Catalogue NumberHCVD6MAG-67K
Trade Name
  • MILLIPLEX
DescriptionMILLIPLEX® MAP Human Cardiovascular Disease Magnetic Bead Panel 6 - Cardiovascular Disease (CVD) Multiplex Assay
OverviewThe MILLIPLEX® MAP Human Cardiovascular Disease Magnetic Bead Panel 6 may be used to simultaneously quantify any or all the the following: Soluble Cluster of Differentiation 14 (sCD14); Dipeptidyl Peptidase-4 (DPP4/DPPIV) / Soluble Cluster of Differentiation 26 (sCD26); Endostatin / Collagen Alpha-1 (XVIII) (COL181A); Progranulin (pGRN) / Proepithelin (PEPI) / PC Cell-derived Growth Factor (PCDGF) / Acrogranin / Paragranulin; Leucine-rich Alpha-2-Glycoprotein 1 (LRG1); Melanoma Cell Adhesion Molecule (MCAM) / Soluble Cluster of Differentiation 146 (sCD146) / Cell Surface Glycoprotein MUC18; Uncarboxylated Matrix Gamma-Carboxyglutamate (Gla) Protein (ucMGP)
Background InformationCardiovascular disease is one of the major causes of death worldwide. Assessing the risk for cardiovascular disease is an important aspect in clinical decision making and setting a therapeutic strategy. The use of serological biomarkers may significantly facilitate risk factor identification. By exploring new applications of established biomarkers and new approaches to identify novel biomarkers, researchers continue to refine the mechanistic understanding of the biology of CVD diseases.
References
Product Information
Detection methodLuminex xMAP
ConfigurationDesign your multiplex kit by choosing available analytes within this panel.
Precision, %
  • sCD14: Intra-assay <5% CV; Inter-assay <20%
  • DPP4/sCD26: Intra-assay <5% CV; Inter-assay <10% CV
  • Endostatin: Intra-assay <5% CV; Inter-assay <10% CV
  • pGRN: Intra-assay <5% CV; Inter-assay <10% CV
  • LRG1: Intra-assay <5% CV; Inter-assay <10% CV
  • MCAM: Intra-assay <5% CV; Inter-assay <10% CV
  • ucMGP: Intra-assay <10% CV; Inter-assay <20% CV
Panel TypeMAGNETIC Cardiovascular
Quality LevelMQ200
Applications
ApplicationThe analytes available for this multiplex kit are: sCD14, DPP4/sCD26, Endostatin, pGRN, LRG1, MCAM, ucMGP
Key Applications
  • Multiplexing
Application NotesFor optimal sensitivity, use an overnight (16-18 hour) incubation. A two hour incubation can also be used (though sensitivity may be lower). Serum and plasma samples require (recommend) a 1:500 dilution with Assay Buffer. Tissue culture supernatants may be run neat or appropriately diluted in control medium. Each well requires 25 μL of sample, standard or control.
Biological Information
SpecificityCross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
Species Reactivity
  • Human
Analytes Available
  • sCD14
  • sCD26
  • Endostatin
  • pGRN
  • LRG1
  • MCAM/sCD146
  • ucMGP
Assay PanelEverything you need in a single kit.
Cross ReactivityThere was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel.
Accuracy
  • sCD14 102%
  • DPP4/sCD26 97%
  • Endostatin 92%
  • pGRN 103%
  • LRG1 103%
  • MCAM 86%
  • ucMGP 95%
Physicochemical Information
Sensitivity
  • MinDC+2SD
  • sCD14: 0.016 ng/mL
  • DPP4: 0.041 ng/mL
  • Endostatin: 0.007 ng/mL
  • pGRN: 0.014 ng/mL
  • LRG1: 0.015 ng/mL
  • MCAM: 0.016 ng/mL
  • ucMGP: 0.052 ng/mL
Linearity of DilutionContact technical support for this information
Standard Curve Range
  • sCD14: 0.01 - 40 ng/mL
  • DPP4/sCD26: 0.049 - 200 ng/mL
  • Endostatin: 0.002 - 10 ng/mL
  • pGRN: 0.024 - 100 ng/mL
  • LRG1: 0.024 -100 ng/mL
  • MCAM: 0.024 - 100 ng/mL
  • ucMGP: 0.049 - 200 ng/mL
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsRecommended storage for kit components is 2 - 8°C.
Packaging Information
Material Size96-well plate
Transport Information
Supplemental Information
Specifications

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Categories

Life Science Research > Protein Detection and Quantification > Immunoassays > Multiplexed Immunoassays > Milliplex MAP Assay Products > Configurable Kits
Life Science Research > Antibodies and Assays > Immunoassays > Multiplexed Immunoassays > Milliplex MAP Assay Products > Configurable Kits