434692 Leukotriene C₄ - CAS 72025-60-6 - Calbiochem

Overview

Replacement Information

Key Specifications Table

Empirical FormulaCAS #
C₃₀H₄₇N₃O₉S 72025-60-6

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434692-50UG
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      Alu drum 50 μg
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      Description
      Overview

      This product has been discontinued.



      Implicated in renal vasoconstriction associated with sepsis. Also plays a role in bronchioconstriction. Produced by conjugation of LTA4 with reduced glutathione. Reported to be a tight binding inhibitor of microsomal glutathione transferase-1. Has been implicated in pathophysiology of asthma.

      Catalogue Number434692
      Brand Family Calbiochem®
      SynonymsLTC₄, 5(S)-Hydroxy-6(R)-S-glutathionyl-7-trans-9-trans-11-cis-14-cis-eicosatetraenoic Acid
      References
      ReferencesBannenberg, G., et al. 1999. J. Biol. Chem. 274, 1994.
      Shimizu, T., et al. 1994. Pediatr. Pulmonol. 18, 129.
      Product Information
      CAS number72025-60-6
      ATP CompetitiveN
      FormLiquid
      FormulationIn MeOH:NH₄OAc buffer (65:35), pH 5.6.
      Hill FormulaC₃₀H₄₇N₃O₉S
      Chemical formulaC₃₀H₄₇N₃O₉S
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetMicrosomal glutathione transferase-1
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSMB9143500
      Safety Information
      R PhraseR: 11-23/24/25-39/23/24/25

      Highly flammable.
      Toxic by inhalation, in contact with skin and if swallowed.
      Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed.
      S PhraseS: 16-7-36/37-45

      Keep away from sources of ignition - No Smoking.
      Keep container tightly closed.
      Wear suitable protective clothing and gloves.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Flammable
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage ≤ -70°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquor and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Leukotriene C₄ - CAS 72025-60-6 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Leukotriene C₄ - CAS 72025-60-6 - Calbiochem Certificates of Analysis

      TitleLot Number
      434692

      References

      Reference overview
      Bannenberg, G., et al. 1999. J. Biol. Chem. 274, 1994.
      Shimizu, T., et al. 1994. Pediatr. Pulmonol. 18, 129.

      Brochure

      Title
      Bioactive Lipids Technical Bulletin
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision14-May-2008 RFH
      SynonymsLTC₄, 5(S)-Hydroxy-6(R)-S-glutathionyl-7-trans-9-trans-11-cis-14-cis-eicosatetraenoic Acid
      DescriptionImplicated in renal vasoconstriction associated with sepsis. Also plays a role in bronchioconstriction. Produced by conjugation of LTA4 with reduced glutathione. Reported to be a tight binding inhibitor of microsomal glutathione transferase-1. Has been implicated in pathophysiology of asthma.
      FormLiquid
      FormulationIn MeOH:NH₄OAc buffer (65:35), pH 5.6.
      CAS number72025-60-6
      RTECSMB9143500
      Chemical formulaC₃₀H₄₇N₃O₉S
      Structure formulaStructure formula
      Purity≥98% by HPLC
      Storage ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquor and freeze (-70°C).
      Toxicity Flammable
      Merck USA index14, 5455
      ReferencesBannenberg, G., et al. 1999. J. Biol. Chem. 274, 1994.
      Shimizu, T., et al. 1994. Pediatr. Pulmonol. 18, 129.