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Description
Overview
A potent agonist of the 5-HT7 serotonin receptor (Ki= 0.22 nM) with good selectivity against other 5-HT receptors (5-HT1A Ki = 52.7 nM, 5-HT1B Ki = 60 nM). Often used in conjuction with the selective 5-HT7 receptor antagonist, SB-269970 (Cat. No. 506415)
Catalogue Number
508155
Brand Family
Calbiochem®
References
References
Monti, J. M. et al. 2008. Behar. Brain Res.191, 184.
Monti, J. M. et al. 2008. Behar. Brain Res.191, 184.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
25-October-2013 JSW
Description
A potent agonist of the 5-HT7 serotonin receptor (Ki= 0.22 nM) with good selectivity against other 5-HT receptors (5-HT1A Ki = 52.7 nM, 5-HT1B Ki = 60 nM). Often used in conjuction with the selective 5-HT7 receptor antagonist, SB-269970 (Cat. No. 506415)
Form
White solid
CAS number
824958-12-5
Chemical formula
C₂₇H₃₈ClN₃OS
Structure formula
Purity
&98% by HPLC
Solubility
DMSO (100 mM) or Ethanol (100 mM0
Storage
+2°C to +8°C
Protect from light
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Standard Handling
References
Monti, J. M. et al. 2008. Behar. Brain Res.191, 184.