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420118 JNK Inhibitor I, (L)-Form, Cell-Permeable, Negative Control - Calbiochem

The JNK Inhibitor I, (L)-Form, Cell-Permeable, Negative Control controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: GRKKRRQRRRPP-NH₂, (L)-HIV-TAT₄₈₋₅₇-PP

Primary Target: A useful negative control for studies involving JNK Inhibitor I, (L)-Form, Cell-Permeable
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420118
  
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      Overview

      Replacement Information

      Key Specifications Table

      Empirical Formula
      C₆₅H₁₂₄N₃₄O₁₃
      Description
      OverviewA highly cell-permeable 10-amino acid carrier peptide derived from HIV-TAT48-57 sequence that is modified with two proline residues. Shown to accumulate into a variety of cells. Serves as a useful negative control for studies involving JNK Inhibitor I, (L)-Form, Cell-Permeable (Cat. No. 420116).
      Catalogue Number420118
      Brand Family Calbiochem®
      SynonymsGRKKRRQRRRPP-NH₂, (L)-HIV-TAT₄₈₋₅₇-PP
      References
      ReferencesBonny, C., et al. 2001. Diabetes 50, 77.
      Vocero-Akbani, A. M., et al 1999. Nat. Med. 5, 29.
      Schwarze, S. R., et al. 1999. Science 285, 1573.
      Nagahara, H., et al. 1998. Nat. Med. 4, 1449.
      Vives, E., et al. 1997. J. Biol. Chem. 272, 16010.
      Product Information
      ATP CompetitiveN
      FormLyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₆₅H₁₂₄N₃₄O₁₃
      Chemical formulaC₆₅H₁₂₄N₃₄O₁₃
      Hygroscopic Hygroscopic
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetA useful negative control for studies involving JNK Inhibitor I, (L)-Form, Cell-Permeable
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableY
      Peptide SequenceH-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Pro-NH₂
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      JNK Inhibitor I, (L)-Form, Cell-Permeable, Negative Control - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      JNK Inhibitor I, (L)-Form, Cell-Permeable, Negative Control - Calbiochem Certificates of Analysis

      TitleLot Number
      420118

      References

      Reference overview
      Bonny, C., et al. 2001. Diabetes 50, 77.
      Vocero-Akbani, A. M., et al 1999. Nat. Med. 5, 29.
      Schwarze, S. R., et al. 1999. Science 285, 1573.
      Nagahara, H., et al. 1998. Nat. Med. 4, 1449.
      Vives, E., et al. 1997. J. Biol. Chem. 272, 16010.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision24-July-2008 RFH
      SynonymsGRKKRRQRRRPP-NH₂, (L)-HIV-TAT₄₈₋₅₇-PP
      DescriptionA highly cell-permeable carrier decapeptide derived from HIV-TAT48-57 sequence that is modified with two proline residues. Serves as a useful negative control for studies involving JNK Inhibitor I, (L)-Form, Cell-permeable (Cat. No. 420116).
      FormLyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₆₅H₁₂₄N₃₄O₁₃
      Peptide SequenceH-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Pro-NH₂
      Purity≥97% by HPLC
      SolubilityH₂O (2 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesBonny, C., et al. 2001. Diabetes 50, 77.
      Vocero-Akbani, A. M., et al 1999. Nat. Med. 5, 29.
      Schwarze, S. R., et al. 1999. Science 285, 1573.
      Nagahara, H., et al. 1998. Nat. Med. 4, 1449.
      Vives, E., et al. 1997. J. Biol. Chem. 272, 16010.