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407952 Ionomycin, Calcium Salt, Streptomyces conglobatus - CAS 56092-82-1 - Calbiochem

Overview

Replacement Information

Key Specifications Table

Empirical FormulaCAS #
C₄₁H₇₀O₉ · Ca 56092-82-1

Pricing & Availability

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407952-10MG
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      407952-1MG
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          407952-25MG
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              Glass bottle 25 mg
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              407952-5MG
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                  Description
                  OverviewUseful in cell activation experiments when calcium dose-response data are not required. Also available as a 10 mM solution in DMSO (Cat. No. 407953).
                  Catalogue Number407952
                  Brand Family Calbiochem®
                  References
                  ReferencesDupuy d'Angeac, A., et al. 1993. J. Cell Physiol. 154, 44.
                  Lee, H.C. 1993. J. Biol. Chem. 268, 293.
                  Product Information
                  CAS number56092-82-1
                  ATP CompetitiveN
                  FormWhite to off-white solid
                  Hill FormulaC₄₁H₇₀O₉ · Ca
                  Chemical formulaC₄₁H₇₀O₉ · Ca
                  ReversibleN
                  Structure formula ImageStructure formula Image
                  Quality LevelMQ100
                  Applications
                  Biological Information
                  Primary TargetUseful in cell activation experiments
                  Purity≥97% by HPLC
                  Physicochemical Information
                  Cell permeableN
                  Dimensions
                  Materials Information
                  Toxicological Information
                  Safety Information according to GHS
                  RTECSNO0650000
                  Safety Information
                  R PhraseR: 22

                  Harmful if swallowed.
                  S PhraseS: 36

                  Wear suitable protective clothing.
                  Product Usage Statements
                  Storage and Shipping Information
                  Ship Code Ambient Temperature Only
                  Toxicity Harmful
                  Storage +2°C to +8°C
                  Protect from Light Protect from light
                  Do not freeze Ok to freeze
                  Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 1 year at 4°C.
                  Packaging Information
                  Packaged under inert gas Packaged under inert gas
                  Transport Information
                  Supplemental Information
                  Specifications

                  Documentation

                  Ionomycin, Calcium Salt, Streptomyces conglobatus - CAS 56092-82-1 - Calbiochem SDS

                  Title

                  Safety Data Sheet (SDS) 

                  Ionomycin, Calcium Salt, Streptomyces conglobatus - CAS 56092-82-1 - Calbiochem Certificates of Analysis

                  TitleLot Number
                  407952

                  References

                  Reference overview
                  Dupuy d'Angeac, A., et al. 1993. J. Cell Physiol. 154, 44.
                  Lee, H.C. 1993. J. Biol. Chem. 268, 293.
                  Data Sheet

                  Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

                  Revision18-February-2010 RFH
                  DescriptionHighly specific for divalent cations (Ca2+ > Mg2+ >> Sr2+ = Ba2+) and more effective than antibiotic A23187 (Cat. No. 100105) as a mobile ion carrier for Ca2+. Complexes with Ca2+ between pH 7 and 9.5, with intense UV absorption. In contrast to A23187, it is not fluorescent. Useful for studies of Ca2+ transport across biological membranes. Induces apoptotic neuronal degeneration in embryonic cortical neurons. Also induces cell cycle arrest in the G1 interval of mature Burkitt lymphoma cell lines. Often used in cell activation experiments when calcium dose-response data is not required.
                  FormWhite to off-white solid
                  Intert gas (Yes/No) Packaged under inert gas
                  CAS number56092-82-1
                  RTECSNO0650000
                  Chemical formulaC₄₁H₇₀O₉ · Ca
                  Structure formulaStructure formula
                  Purity≥97% by HPLC
                  SolubilityDMSO (100 mg/ml)
                  Storage +2°C to +8°C
                  Protect from light
                  Do Not Freeze Ok to freeze
                  Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 1 year at 4°C.
                  Toxicity Harmful
                  ReferencesDupuy d'Angeac, A., et al. 1993. J. Cell Physiol. 154, 44.
                  Lee, H.C. 1993. J. Biol. Chem. 268, 293.

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                  Categories

                  Life Science Research > Inhibitors and Biochemicals > Biochemicals > Ionophores