407711 Interleukin-12, Human, Recombinant, S. frugiperda

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407711
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407711-5UG
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      Plastic ampoule 5 μg
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      Description
      OverviewRecombinant, human interleukin-12 expressed in S. frugiperda insect cells. Pleiotropic cytokine that is produced by monocytes/macrophages, B cells, and connective tissue-type mast cells. Also known as natural killer cell stimulatory factor and cytotoxic lymphocyte maturation factor. A potent inducer of IFN-γ production and T cell differentiation and function.
      Catalogue Number407711
      Brand Family Calbiochem®
      SynonymsrhIL-12
      References
      ReferencesKang, K., et al. 1996. J. Immunol. 156, 1402.
      Riemann, H., et al. 1996. J. Immunol. 156, 1799.
      Brunda, M.J., et al. 1994. J. Leukoc. Biol. 55, 280.
      Smith, T.J., et al. 1994. Eur. J. Immunol. 24, 822.
      Gubler, U., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 4143.
      Stern, A.S., et al. 1990. Proc. Natl. Acad. Sci. USA 87, 6808.
      Kobayashi, M., et al. 1989. J. Exp. Med. 170, 827.
      Product Information
      FormLyophilized
      FormulationLyophilized from sterile-filtered PBS, 50 µg BSA/µg IL-12.
      Quality LevelMQ100
      Applications
      Biological Information
      Biological activityED₅₀ = 50-200 pg/ml as measured by its ability to stimulate the proliferation of PHA-activated human lymphoblasts
      Purity≥95% by SDS-PAGE
      Physicochemical Information
      ContaminantsEndotoxin: ≤1.0 EU/µg IL-12
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 month at 4°C. Avoid freeze/thaw cycles of solutions.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Interleukin-12, Human, Recombinant, S. frugiperda SDS

      Title

      Safety Data Sheet (SDS) 

      Interleukin-12, Human, Recombinant, S. frugiperda Certificates of Analysis

      TitleLot Number
      407711

      References

      Reference overview
      Kang, K., et al. 1996. J. Immunol. 156, 1402.
      Riemann, H., et al. 1996. J. Immunol. 156, 1799.
      Brunda, M.J., et al. 1994. J. Leukoc. Biol. 55, 280.
      Smith, T.J., et al. 1994. Eur. J. Immunol. 24, 822.
      Gubler, U., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 4143.
      Stern, A.S., et al. 1990. Proc. Natl. Acad. Sci. USA 87, 6808.
      Kobayashi, M., et al. 1989. J. Exp. Med. 170, 827.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision23-July-2008 RFH
      SynonymsrhIL-12
      DescriptionRecombinant, human interleukin-12 expressed in S. frugiperda insect cells. Pleiotropic cytokine that is produced by monocytes/macrophages, B-cells, and connective tissue type mast cells. Also known as natural killer cell stimulatory factor and cytotoxic lymphocyte maturation factor. A potent inducer of IFN-γ production and T-cell differentiation and function.
      FormLyophilized
      FormulationLyophilized from sterile-filtered PBS, 50 µg BSA/µg IL-12.
      Purity≥95% by SDS-PAGE
      ContaminantsEndotoxin: ≤1.0 EU/µg IL-12
      Biological activityED₅₀ = 50-200 pg/ml as measured by its ability to stimulate the proliferation of PHA-activated human lymphoblasts
      SolubilityReconstitute to a concentration ≥1 µg/ml with sterile PBS containing at least 0.1% HSA or BSA.
      Storage ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 month at 4°C. Avoid freeze/thaw cycles of solutions.
      Toxicity Standard Handling
      ReferencesKang, K., et al. 1996. J. Immunol. 156, 1402.
      Riemann, H., et al. 1996. J. Immunol. 156, 1799.
      Brunda, M.J., et al. 1994. J. Leukoc. Biol. 55, 280.
      Smith, T.J., et al. 1994. Eur. J. Immunol. 24, 822.
      Gubler, U., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 4143.
      Stern, A.S., et al. 1990. Proc. Natl. Acad. Sci. USA 87, 6808.
      Kobayashi, M., et al. 1989. J. Exp. Med. 170, 827.