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344041 InSolution™ cFMS Receptor Tyrosine Kinase Inhibitor - Calbiochem

Overview

Replacement Information

Key Specifications Table

Empirical Formula
C₂₀H₂₂N₄O₃

Pricing & Availability

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344041-1MG
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      Glass bottle 1 mg
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      Description
      Catalogue Number344041
      Brand Family Calbiochem®
      References
      ReferencesConway, J.G., et al. 2005. Proc. Natl. Acad. Sci. USA 102, 16078.
      Product Information
      FormLiquid
      FormulationA 10 mM (1 mg/273 µl) solution of cFMS Receptor Tyrosine Kinase Inhibitor (Cat. No. 344036) in DMSO.
      Hill FormulaC₂₀H₂₂N₄O₃
      Chemical formulaC₂₀H₂₂N₄O₃
      Hygroscopic Hygroscopic
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/38

      Irritating to eyes and skin.
      S PhraseS: 26-36-45

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped with Blue Ice or with Dry Ice
      Toxicity Irritant
      Storage -20°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      InSolution™ cFMS Receptor Tyrosine Kinase Inhibitor - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      InSolution™ cFMS Receptor Tyrosine Kinase Inhibitor - Calbiochem Certificates of Analysis

      TitleLot Number
      344041

      References

      Reference overview
      Conway, J.G., et al. 2005. Proc. Natl. Acad. Sci. USA 102, 16078.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision19-December-2008 JSW
      DescriptionA cell-permeable diaminopyrimidine compound that acts as a potent, selective, and ATP-competitive inhibitor of cFMS kinase activity (IC50 = 30 nM) with minimal inhibition towards a panel of 26 other kinases (IC50 >5 µM). Shown to selectively inhibit cFMS-mediated cellular functions in vitro as well as CSF-1-dependent tumor growth in vivo.
      FormLiquid
      FormulationA 10 mM (1 mg/273 µl) solution of cFMS Receptor Tyrosine Kinase Inhibitor (Cat. No. 344036) in DMSO.
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₂₀H₂₂N₄O₃
      Structure formulaStructure formula
      Purity≥95% by HPLC
      Storage -20°C
      Hygroscopic
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Irritant
      ReferencesConway, J.G., et al. 2005. Proc. Natl. Acad. Sci. USA 102, 16078.