557521 Sigma-AldrichInSolution™ Ro-31-8220 - Calbiochem
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Primary Target:
PKC
InSolution™ Ro-31-8220 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: 3-[1-[3-(Amidinothio)propyl-1H-indol-3-yl]-3-(1-methyl-1H-indol-3-yl)maleimide, Bisindolylmaleimide IX, Methanesulfonate
Recommended Products
Overview
| Replacement Information |
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Key Specifications Table
| Empirical Formula |
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| C₂₅H₂₃N₅O₂S • CH₃SO₃H |
Pricing & Availability
| Catalog Number | Availability | Packaging | Qty/Pack | Price | Quantity | |
|---|---|---|---|---|---|---|
| 557521-500UG |
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Plastic ampoule | 500 μg |
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| Description | |
|---|---|
| Catalogue Number | 557521 |
| Brand Family | Calbiochem® |
| Synonyms | 3-[1-[3-(Amidinothio)propyl-1H-indol-3-yl]-3-(1-methyl-1H-indol-3-yl)maleimide, Bisindolylmaleimide IX, Methanesulfonate |
| References |
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| Product Information | |
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| ATP Competitive | Y |
| Form | Clear orange-brown liquid |
| Formulation | A 5 mM (500 µg/181 µl) solution of Ro-31-8220 (Cat. No. 557520) in H₂O. |
| Hill Formula | C₂₅H₂₃N₅O₂S • CH₃SO₃H |
| Chemical formula | C₂₅H₂₃N₅O₂S • CH₃SO₃H |
| Reversible | Y |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | PKC |
| Primary Target IC<sub>50</sub> | 10 nM against protein kinase C (PKC); 6.8 nM against GSK-3 in primary adipocytes |
| Purity | ≥95% by HPLC |
| Physicochemical Information | |
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| Cell permeable | Y |
| Dimensions |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information |
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| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
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| Supplemental Information |
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| Specifications |
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Documentation
InSolution™ Ro-31-8220 - Calbiochem SDS
| Title |
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InSolution™ Ro-31-8220 - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 557521 |
Brochure
| Title |
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| In Solution! Product Flyer |
| PKC Pathway Poster PDF ( 676 KB ) |
Citations
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| Data Sheet | ||||||||||||||||||||||||||||
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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