540223 InSolution™ Purmorphamine - Calbiochem

Overview

Replacement Information

Key Specifications Table

Empirical Formula
C₃₁H₃₂N₆O₂

Pricing & Availability

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540223-5MG
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      Plastic ampoule 5 mg
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      Description
      Catalogue Number540223
      Brand Family Calbiochem®
      References
      ReferencesWu, X., et al. 2004. Chem. Biol. 11, 1229.
      Wu, X., et al. 2002. J. Am. Chem. Soc. 124, 14520.
      Product Information
      FormLiquid
      FormulationA 50 mM (5 mg/192 µl) solution of Purmorphamine (Cat. No. 540220) in DMSO.
      Hill FormulaC₃₁H₃₂N₆O₂
      Chemical formulaC₃₁H₃₂N₆O₂
      Hygroscopic Hygroscopic
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      ApplicationInSolution™ Purmorphamine, CAS 483367-10-8, is a provided as a 50 mM solution in DMSO. Induces osteoblast differentiation of multipotent mesenchymal progenitor cells C3H10T1/2 & lineage-committed preosteoblasts MC3T3-E1.
      Biological Information
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/38

      Irritating to eyes and skin.
      S PhraseS: 26-36-45

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped with Blue Ice or with Dry Ice
      Toxicity Irritant
      Storage -20°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      InSolution™ Purmorphamine - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      InSolution™ Purmorphamine - Calbiochem Certificates of Analysis

      TitleLot Number
      540223

      References

      Reference overview
      Wu, X., et al. 2004. Chem. Biol. 11, 1229.
      Wu, X., et al. 2002. J. Am. Chem. Soc. 124, 14520.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision26-August-2008 JSW
      DescriptionA cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells (EC50 = 1 µM) and in MC3T3-E1 lineage-committed preosteoblasts. Also shown to induce transdifferentiation in pre-adipocytes and myoblasts. Its effects are reported to be synergistic with bone morphogenetic protein-4 (BMP-4). Reported to induce osteogenesis by activation of the Hedgehog signaling pathway.
      FormLiquid
      FormulationA 50 mM (5 mg/192 µl) solution of Purmorphamine (Cat. No. 540220) in DMSO.
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₃₁H₃₂N₆O₂
      Structure formulaStructure formula
      Purity≥98% by HPLC
      Storage -20°C
      Hygroscopic
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Irritant
      ReferencesWu, X., et al. 2004. Chem. Biol. 11, 1229.
      Wu, X., et al. 2002. J. Am. Chem. Soc. 124, 14520.