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508573 InSolution™ PPACK II, 2TFA - CAS 649748-23-2 - Calbiochem

A 10 mM (5 mg/686 µl) sterile-filtered solution of PPACK II, 2TFA in H₂O.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: D-Phenylalanyl-L-phenylalanyl-L-arginine chloromethyl ketone, 2TFA, H-D-Phe-Phe-Arg-chloromethylketone, 2TFA, PPACK II, Trifluoroacetate Salt InSolution™

Primary Target: thrombin
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508573
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
649748-23-2C₂₅H₃₃ClN₆O₃ • 2CF₃CO₂H

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      Description
      Catalogue Number508573
      Brand Family Calbiochem®
      SynonymsD-Phenylalanyl-L-phenylalanyl-L-arginine chloromethyl ketone, 2TFA, H-D-Phe-Phe-Arg-chloromethylketone, 2TFA, PPACK II, Trifluoroacetate Salt InSolution™
      References
      ReferencesByrne, R.E., and Scanu, A.M. 1989. J. Lipid Res. 30, 109.
      Scicli, G., et al. 1989. Adv. Exp. Med. Biol. 247B, 217.
      Gibson, T.R., et al. 1987. Endocrinology 120, 764.
      Kettner, G., and Shaw, E. 1981. Methods Enzymol. 80, 826.
      Product Information
      CAS number649748-23-2
      FormLiquid
      FormulationA 10 mM (5 mg/686 µl) sterile-filtered solution of PPACK II, 2TFA (Cat. No. 520219) in H₂O.
      Hill FormulaC₂₅H₃₃ClN₆O₃ • 2CF₃CO₂H
      Chemical formulaC₂₅H₃₃ClN₆O₃ • 2CF₃CO₂H
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Target thrombin
      Secondary targetplasma and glandular kallikreins
      Purity≥95% by HPLC
      Physicochemical Information
      Peptide SequenceH-D-Phe-Phe-Arg-chloromethylketone, 2TFA
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Regulatory Review
      Storage ≤ -70°C
      Protect from Light Protect from light
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      InSolution™ PPACK II, 2TFA - CAS 649748-23-2 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Byrne, R.E., and Scanu, A.M. 1989. J. Lipid Res. 30, 109.
      Scicli, G., et al. 1989. Adv. Exp. Med. Biol. 247B, 217.
      Gibson, T.R., et al. 1987. Endocrinology 120, 764.
      Kettner, G., and Shaw, E. 1981. Methods Enzymol. 80, 826.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-August-2020 JSW
      SynonymsD-Phenylalanyl-L-phenylalanyl-L-arginine chloromethyl ketone, 2TFA, H-D-Phe-Phe-Arg-chloromethylketone, 2TFA, PPACK II, Trifluoroacetate Salt InSolution™
      DescriptionPotent and specific irreversible inhibitor of plasma and glandular kallikreins. Inhibits the cleavage of atrial naturiuretic peptide (ANP 1-126) by kallikreins. Also inhibits adrenal kininogenase, a kallikrein-like enzyme.
      FormLiquid
      FormulationA 10 mM (5 mg/686 µl) sterile-filtered solution of PPACK II, 2TFA (Cat. No. 520219) in H₂O.
      Intert gas (Yes/No) Packaged under inert gas
      CAS number649748-23-2
      Chemical formulaC₂₅H₃₃ClN₆O₃ • 2CF₃CO₂H
      Peptide SequenceH-D-Phe-Phe-Arg-chloromethylketone, 2TFA
      Purity≥95% by HPLC
      Storage Protect from light
      Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
      Toxicity Regulatory Review
      ReferencesByrne, R.E., and Scanu, A.M. 1989. J. Lipid Res. 30, 109.
      Scicli, G., et al. 1989. Adv. Exp. Med. Biol. 247B, 217.
      Gibson, T.R., et al. 1987. Endocrinology 120, 764.
      Kettner, G., and Shaw, E. 1981. Methods Enzymol. 80, 826.