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509281 InSolution™ Leupeptin, Hemisulfate, Microbial - CAS 103476-89-7 - Calbiochem

509281
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Overview

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Key Specifications Table

Empirical FormulaCAS #
C₂₀H₃₈N₆O₄ • 1/2(H2SO4) 103476-89-7

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      Description
      OverviewThe recommended working range is 10-100 µM for most applications.
      Catalogue Number509281
      Brand Family Calbiochem®
      SynonymsAc-LLR-CHO, 1/2(H2SO4), Ac-Leu-Leu-arginal, hemisulfate
      References
      ReferencesMontenez, J.P., et al. 1994. Toxicol. Lett. 73, 201.
      Sarin, A., et al. 1994. J. Immunol. 153, 862.
      Product Information
      CAS number103476-89-7
      FormLiquid
      FormulationA 50 mM (10 mg/421 µl) sterile-filtered solution of Leupeptin, Hemisulfate, Microbial (Cat. No. 108975) in H₂O.
      Hill FormulaC₂₀H₃₈N₆O₄ • 1/2(H2SO4)
      Chemical formulaC₂₀H₃₈N₆O₄ • 1/2(H2SO4)
      ReversibleY
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targettrypsin-like proteases and cysteine proteases
      Purity≥90% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide SequenceAc-Leu-Leu-arginal, hemisulfate
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Protect from Light Protect from light
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      References

      Reference overview
      Montenez, J.P., et al. 1994. Toxicol. Lett. 73, 201.
      Sarin, A., et al. 1994. J. Immunol. 153, 862.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision11-April-2014 JSW
      SynonymsAc-LLR-CHO, 1/2(H2SO4), Ac-Leu-Leu-arginal, hemisulfate
      DescriptionA reversible inhibitor of trypsin-like proteases and cysteine proteases. Also known to inhibit activation-induced programmed cell death and to restore defective immune response in HIV+ donors. Often used for the inhibition of endoproteinase Lys-C, kallikrein, papain, plasmin, thrombin, cathepsin B, and trypsin. Leupeptin does not inhibit chymotrypsin, elastase, renin, or pepsin. The recommended working range is 10-100 µM for most applications.
      FormLiquid
      FormulationA 50 mM (10 mg/421 µl) sterile-filtered solution of Leupeptin, Hemisulfate, Microbial (Cat. No. 108975) in H₂O.
      Intert gas (Yes/No) Packaged under inert gas
      CAS number103476-89-7
      Chemical formulaC₂₀H₃₈N₆O₄ • 1/2(H2SO4)
      Peptide SequenceAc-Leu-Leu-arginal, hemisulfate
      Purity≥90% by HPLC
      Storage ≤ -70°C
      Protect from light
      Avoid freeze/thaw
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesMontenez, J.P., et al. 1994. Toxicol. Lett. 73, 201.
      Sarin, A., et al. 1994. J. Immunol. 153, 862.