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GF446-10UG HumanKine® Thermostable bFGF,
Human Recombinant

GF446-10UG
10 µg  
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      Overview

      Replacement Information

      Key Specifications Table

      SourcePurity
      HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.Product is endotoxin free (<0.5 ng/μg of protein (<5 EU/μg) and greater than 95% pure by SDS-PAGE.
      Description
      Catalogue NumberGF446-10UG
      Trade Name
      • HumanKine®
      DescriptionHumanKine® Thermostable bFGF,
      Human Recombinant
      Alternate Names
      • FGF2
      • prostatropin
      • Prostatropin
      • HBGF-2
      • BFGF
      Background InformationThe HumanKine Thermostable bFGF is engineered with enchanced thermostability compared to the wild-type bFGF protein without modification of biological function.

      Fibroblast Growth Factor-basic (bFGF) is a heparin binding growth factor which stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells. bFGF also exerts a potent angiogenic activity in vivo. Human bFGF is a 17.2 kDa protein containing 154 amino acid residues. bFGF synergizes with the BMP antagonist noggin to sustain undifferentiated proliferation of human embryonic stem (hES) cells under feeder-free conditions.
      References
      Product Information
      PresentationProduct is filtered through a 0.2 micron filter before lyophilization.
      Quality LevelMQ100
      Applications
      ApplicationEngineered bFGF growth factor with enchanced thermostability compared to the wild-type bFGF protein. Allows a less vigorous feeding schedule for human es/ips and neural stem cell culture.
      Application NotesHumanKine products are Xeno-Free
      Biological Information
      PurityProduct is endotoxin free (<0.5 ng/μg of protein (<5 EU/μg) and greater than 95% pure by SDS-PAGE.
      SourceHumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceBioactivity assay: Determined by the dose-dependent stimulation of the proliferation of the 3T3 cell line. ED50 is typically <0.5 ng/mL.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C for up to 4 months from date of receipt. Further dilutions should be made into appropriate buffer or medium to which protein has been added.
      Packaging Information
      Material Size10 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      HumanKine® Thermostable bFGF,
      Human Recombinant SDS

      Title

      Safety Data Sheet (SDS) 

      HumanKine® Thermostable bFGF,
      Human Recombinant Certificates of Analysis

      TitleLot Number
      HumanKine® Thermostable bFGF, Human Recombinant - QVP1402050 QVP1402050
      HumanKine® Thermostable bFGF, Human Recombinant - VP1403190 VP1403190
      HumanKine® Thermostable bFGF, Human Recombinant - VP1405055 VP1405055
      HumanKine® Thermostable bFGF, -VP1602127 VP1602127
      HumanKine® Thermostable bFGF, -VP1603019 VP1603019
      HumanKine® Thermostable bFGF, -VP1604187 VP1604187
      HumanKine® Thermostable bFGF, -VP1607192 VP1607192
      HumanKine® Thermostable bFGF, Human Recombinant - VP1811285 VP1811285
      HumanKine® Thermostable bFGF, Human Recombinant - VP1906262 VP1906262
      HumanKine® Thermostable bFGF, Human Recombinant - VP1910312 VP1910312

      Technical Info

      Title
      HumanKine® Thermostable bFGF, an engineered recombinant protein with enhanced biological functionality on human iPS and neural progenitor cells