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EZHS100B-33K Human S100B ELISA, EZHS100B-33K

EZHS100B-33K
96-well strip plate  
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      Overview

      Replacement Information

      Key Specifications Table

      Analytes AvailableSpecies ReactivityKey Applications
      S100B HELISA
      Description
      Catalogue NumberEZHS100B-33K
      DescriptionHuman S100B ELISA, EZHS100B-33K
      OverviewEMD Millipore’s Human S100B ELISA kit is to be used for the quantification of human S100B in cerebrospinal fluid, serum and plasma. This kit has not been tested for cell culture supernatants.
      Background InformationS100B is a calcium-binding protein produced mainly by astrocytes in the central nervous system and has been implicated in the development and maintenance of the nervous system. Although the mechanism of S100B secretion is unknown, it appears to be affected by oxidative stress. At nanomolar concentrations (normal levels), S100B is able to protect neurons against glutamate toxicity. Glial damage or astrocytic reactions to neural injury (reactive astrogliosis) causes an increase in S100B to micromolar concentrations. High levels of S100B will further increase neuronal damage. High levels of S100B are considered a biomarker that could indicate damage or dysfunction of CNS.
      References
      Product Information
      Precision, %
      • Intra-assay: <4%
      • Inter-assay: <4%
      Quality LevelMQ100
      Applications
      ApplicationThis Human S100B ELISA kit is to be used for the quantification of human S100B in cerebrospinal fluid, serum & plasma.
      Key Applications
      • ELISA
      Application NotesThis is a same day assay
      Biological Information
      SpecificityThe antibody pair used in this assay measures Human S100B and has no cross-reactivity with S100A1, S100A6 and S100A13.

      This assay detects S100B in multiple species, including: bovine, hamster, horse, monkey, mouse, pig, rabbit, and rat.
      Species Reactivity
      • Human
      Analytes Available
      • S100B
      UniProt Number
      Accuracy
      • 93% (CSF)
      • 94% (serum)
      Physicochemical Information
      Sensitivity
      • 2.7 pg/mL
      Linearity of DilutionContact Technical Service for this information
      Standard Curve Range
      • 2.7 – 2000 pg/mL
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • For research use only. Not for use in diagnostic procedures.
      Storage and Shipping Information
      Packaging Information
      Material Size96-well strip plate
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Protocols

      Title
      Protocol: Human S100B ELISA

      Human S100B ELISA, EZHS100B-33K SDS

      Title

      Safety Data Sheet (SDS) 

      Brochure

      Title
      A closer look at immunoassay platforms. Beyond fit for purpse. Bring your biomarkers to life with EMD Millipore Immunoassay Platform Solutions (SigmaMillipore)
      Protein Detection Platform and Services Brochure

      Technical Info

      Title
      96 well Template 2 Up
      96 well Template Single
      Quality Control Ranges: HUMAN S100B ELISA

      Data Sheet

      Title
      Full Service Custom-built Assays (MilliporeSigma)