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PYYT-66HK Human PYY (Total) RIA

PYYT-66HK
125 tubes  
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      Overview

      Replacement Information

      Key Specifications Table

      Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
      PYY H RIA Radioactive, 125I
      Description
      Catalogue NumberPYYT-66HK
      DescriptionHuman PYY (Total) RIA
      Background InformationPeptide YY (PYY), a 36-amino acid amidated peptide, is a member of PP family including pancreatic polypeptide (PP) and neuropeptide Y (NPY).
      References
      Product Information
      Detection methodRadioactive 125I
      Performance
      • ED80 = 37.2 ± 8 pg/mL
      • ED50 = 110.9 ± 20 pg/mL
      • ED20 = 333.8 ± 73 pg/mL
      Precision, %
      • Inter-assay: 5.5–8.5
      • Intra-assay: 2.9–9.4
      Quality LevelMQ100
      Applications
      ApplicationThis radioimmunoassay (RIA) measures & quantifies PYY for use in Metabolism & Endocrine & Neuroscience research.
      Key Applications
      • Radioimmunoassay
      Application NotesTwo-day disequilibrium assay, incubation at 4°C Sample volume: 100 μL serum, plasma, or tissue culture sample
      Biological Information
      SpecificityHuman Pyy 1-36 100% Human PYY 3-36 100% [Pro34] PYY 100%[Leu31, Pro34] PYY 100% Rat/Porcine PYY 1-36 <0.1% Rat/Porcine PYY 3-36 <0.1% Human PP < 0.1% Human NPY <0.1% Human Leptin Not detectable Human Ghrelin Not detectable Human Insulin No
      Species Reactivity
      • Human
      Analytes Available
      • PYY
      Entrez Gene Number
      Gene Symbol
      • PYY
      • PYY-I
      • PYY1
      Radioactive Isotype125I-PYY
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P10082 # This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.
      SIZE: 97 amino acids; 11046 Da
      SUBCELLULAR LOCATION: Secreted.
      SIMILARITY: SwissProt: P10082 ## Belongs to the NPY family.
      Accuracy
      • 83–111%
      Physicochemical Information
      Sensitivity
      • 10 pg/mL
      Standard Curve Range
      • 10–1280 pg/mL
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size125 tubes
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Protocols

      Title
      Protocol: Human PYY (Total) RIA Kit

      Human PYY (Total) RIA SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overviewPub Med ID
      Length and site of the small intestine exposed to fat influences hunger and food intake.
      P W Jeroen Maljaars,Harry P F Peters,Andrea Kodde,Maartje Geraedts,Fred J Troost,Edward Haddeman,Ad A M Masclee
      The British journal of nutrition  106  2011

      Show Abstract
      21736790 21736790
      Effect of overweight on gastrointestinal microbiology and immunology: correlation with blood biomarkers.
      Kirsti Tiihonen,Arthur C Ouwehand,Nina Rautonen
      The British journal of nutrition  103  2010

      Show Abstract
      19930761 19930761

      Brochure

      Title
      A closer look at immunoassay platforms. Beyond fit for purpse. Bring your biomarkers to life with EMD Millipore Immunoassay Platform Solutions (SigmaMillipore)
      Analyte Quarterly Vol. 2 2020
      ELISAs, RIAs & GyroMark HT Assays
      Protein Detection Platform and Services Brochure

      Technical Info

      Title
      Quality Control Ranges: Human PYY (Total) RIA Kit, Human PYY (3-36) RIA Kit

      Data Sheet

      Title
      Full Service Custom-built Assays (MilliporeSigma)

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      Categories

      Life Science Research > Protein Detection and Quantification > Immunoassays > Radioimmunoassay (RIA) > Complete RIA Kits
      Life Science Research > Antibodies and Assays > Immunoassays > Radioimmunoassay (RIA) > Complete RIA Kits