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PYY-67HK Human PYY (3-36) Specific RIA

PYY-67HK
125 tubes  
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      Overview

      Replacement Information

      Key Specifications Table

      Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
      PYY HRIARadioactive 125I
      Description
      Catalogue NumberPYY-67HK
      DescriptionHuman PYY (3-36) Specific RIA
      Background InformationPeptide YY (PYY), a novel 36 amino-acid amidated hormone is a component of the complex neuroendocrine control process.
      References
      Product Information
      Detection methodRadioactive 125I
      Performance
      • ED80 = 93 ± 3 pg/mL
      • ED50 = 230 ± 15 pg/mL
      • ED20 = 558 ± 44 pg/mL
      Precision, %
      • Inter-assay: 6–11
      • Intra-assay: 7–15
      Quality LevelMQ100
      Applications
      ApplicationThis radioimmunoassay (RIA) measures & quantifies PYY for use in Metabolism & Endocrine & Neuroscience research.
      Key Applications
      • Radioimmunoassay
      Application NotesTwo-day disequilibrium assay, incubation at 4°C Sample volume: 100 μL serum, plasma, or tissue culture sample
      Biological Information
      SpecificityHuman PYY (3-36) 100% Human PYY (1-36) Not Detectable
      Species Reactivity
      • Human
      Analytes Available
      • PYY
      Entrez Gene Number
      Gene Symbol
      • PYY
      • PYY-I
      • PYY1
      Radioactive Isotype125I-PYY
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P10082 # This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.
      SIZE: 97 amino acids; 11046 Da
      SUBCELLULAR LOCATION: Secreted.
      SIMILARITY: SwissProt: P10082 ## Belongs to the NPY family.
      Accuracy
      • 94.5 ± 10.2%
      Physicochemical Information
      Sensitivity
      • 20 pg/mL
      Linearity of Dilution80–120%
      Standard Curve Range
      • 20–1280 pg/mL
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size125 tubes
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Protocols

      Title
      Protocol: Human PYY (3-36) Specific RIA Kit

      Human PYY (3-36) Specific RIA SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overviewPub Med ID
      Differential Acylated Ghrelin, Peptide YY3-36, Appetite, and Food Intake Responses to Equivalent Energy Deficits Created by Exercise and Food Restriction.
      King, James A, et al.
      J. Clin. Endocrinol. Metab., 96: 1114-21 (2011)  2011

      Show Abstract
      21270331 21270331
      Oat beta-glucan supplementation does not enhance the effectiveness of an energy-restricted diet in overweight women.
      Eleanor J Beck,Linda C Tapsell,Marijka J Batterham,Susan M Tosh,Xu-Feng Huang
      The British journal of nutrition  103  2010

      Show Abstract
      19930764 19930764
      Mastication of almonds: effects of lipid bioaccessibility, appetite, and hormone response.
      Bridget A Cassady, James H Hollis, Angie D Fulford, Robert V Considine, Richard D Mattes
      The American journal of clinical nutrition  89  794-800  2009

      Show Abstract
      19144727 19144727
      Inhibition of renal dipeptidyl peptidase IV enhances peptide YY1-36-induced potentiation of angiotensin II-mediated renal vasoconstriction in spontaneously hypertensive rats.
      Edwin K Jackson, Mingdi Zhang, Weili Liu, Zaichuan Mi
      The Journal of pharmacology and experimental therapeutics  323  431-7  2007

      Show Abstract
      17726157 17726157

      Brochure

      Title
      A closer look at immunoassay platforms. Beyond fit for purpse. Bring your biomarkers to life with EMD Millipore Immunoassay Platform Solutions (SigmaMillipore)
      Analyte Quarterly Vol. 2 2020
      ELISAs, RIAs & GyroMark HT Assays
      Protein Detection Platform and Services Brochure

      Technical Info

      Title
      Quality Control Ranges: Human PYY (Total) RIA Kit, Human PYY (3-36) RIA Kit

      Data Sheet

      Title
      Full Service Custom-built Assays (MilliporeSigma)

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      Categories

      Life Science Research > Protein Detection and Quantification > Immunoassays > Radioimmunoassay (RIA) > Complete RIA Kits
      Life Science Research > Antibodies and Assays > Immunoassays > Radioimmunoassay (RIA) > Complete RIA Kits