Millipore Sigma Vibrant Logo

GHRT-89HK Human Ghrelin (TOTAL) RIA

GHRT-89HK
125 tubes  
Retrieving price...
Price could not be retrieved
Minimum Quantity is a multiple of
Maximum Quantity is
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited Availability
Limited Availability
Stocked 
Discontinued
Limited Quantities Available
Available
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

       

      Contact Customer Service

      Overview

      Replacement Information

      Key Specifications Table

      Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
      Ghrelin HRIARadioactive 125I
      Description
      Catalogue NumberGHRT-89HK
      DescriptionHuman Ghrelin (TOTAL) RIA
      Background InformationGhrelin is a recently discovered hormone is secreted primarily by the stomach in response to glucose administration or CNS signals.
      References
      Product Information
      Detection methodRadioactive 125I
      Performance
      • ED80 = 395 ± 88 pg/mL
      • ED50 = 895 ± 177 pg/mL
      • ED20 = 2015 ± 382 pg/mL
      Precision, %
      • Inter-assay: 14.7–17.8
      • Intra-assay: 3.3–10.0
      Quality LevelMQ100
      Applications
      ApplicationThis radioimmunoassay (RIA) measures & quantifies Ghrelin for use in Metabolism & Endocrine & Neuroscience research.
      Key Applications
      • Radioimmunoassay
      Application NotesTwo-day disequilibrium assay at 4°C. Sample volume: < 100 μL Plasma (collected on ice) recommended
      Biological Information
      Species Reactivity
      • Human
      Analytes Available
      • Ghrelin
      Entrez Gene Number
      Entrez Gene SummaryGhrelin is an endogenous ligand for the growth hormone secretagogue receptor (GHSR; MIM 601898) and is involved in regulating growth hormone (GH; MIM 139250) release. Ghrelin is derived from a preprohormone called preproghrelin, which also generates a second peptide called obestatin. Obestatin is an endogenous ligand for the orphan G protein-coupled receptor GPR39 (MIM 602886) and is involved in satiety and decreased food intake.[supplied by OMIM]
      Gene Symbol
      • GHRL
      • ghrelin
      • MTLRP
      • obestatin
      Radioactive Isotype125I-Human Ghrelin
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q9UBU3 # Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility (By similarity).
      SIZE: 117 amino acids; 12911 Da
      SUBCELLULAR LOCATION: Secreted.
      TISSUE SPECIFICITY: Highest level in stomach. All forms are found in serum as well. Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy.
      PTM: O-octanoylation or O-decanoylation is essential for ghrelin activity. The O-decanoylated forms Ghrelin-27-C10 and Ghrelin-28- C10 differ in the length of the carbon backbone of the carboxylic acid bound to Ser-26. A small fraction of ghrelin, ghrelin-28- C10:1, may be modified with a singly unsaturated carboxylic acid. & Amidation of Leu-98 is essential for obestatin activity (By similarity).
      SIMILARITY: SwissProt: Q9UBU3 ## Belongs to the motilin family.
      Accuracy
      • 90–96%
      Physicochemical Information
      Sensitivity
      • 100–10,000 pg/mL
      Linearity of Dilution99–146%
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size125 tubes
      Transport Information
      Supplemental Information
      Specifications

      Related Products & Applications

      Related Products

      Catalog Number Description  
      EZGRT-89BK Human Ghrelin (total) ELISA- Bulk Show Pricing & Availability
      EZGRT-89K Human Ghrelin (total) ELISA Show Pricing & Availability
      GHRA-88HK Human Ghrelin (ACTIVE) RIA Show Pricing & Availability
      HMHEMAG-34K MILLIPLEX MAP Human Metabolic Hormone Magnetic Bead Panel - Metabolism Multiplex Assay Show Pricing & Availability

      Categories

      Life Science Research > Antibodies and Assays > Immunoassays > Radioimmunoassay (RIA) > Complete RIA Kits
      Life Science Research > Protein Detection and Quantification > Immunoassays > Radioimmunoassay (RIA) > Complete RIA Kits