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368059 Granzyme B Substrate II, Fluorogenic - Calbiochem

368059
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Overview

Replacement Information

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Catalog Number AvailabilityPackaging Qty/Pack Price Quantity
368059-1MG
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      368059-5MG
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      Stocked 
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      Limited Quantities Available
      Available
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          Remaining : Will advise
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          Plastic ampoule 5 mg
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          Description
          OverviewA fluorogenic substrate for the detection of granzyme B and caspase-8 activity. Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore.
          Catalogue Number368059
          Brand Family Calbiochem®
          SynonymsZ-IETD-AFC, Caspase-8 Substrate II
          References
          ReferencesKarahashi, H., and Amano, F. 2000. Biol. Pharm. Bull. 23, 140.
          Product Information
          ATP CompetitiveN
          FormWhite lyophilized solid
          Hill FormulaC₃₇H₄₂F₃N₅O₁₃
          Chemical formulaC₃₇H₄₂F₃N₅O₁₃
          ReversibleN
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetFluorogenic substrate for the detection of granzyme B and caspase-8 activity
          Purity≥97% by HPLC
          Physicochemical Information
          Cell permeableN
          Emission max.
          Excitation max.
          Peptide SequenceZ-Ile-Glu-Thr-Asp-AFC
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Granzyme B Substrate II, Fluorogenic - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          Granzyme B Substrate II, Fluorogenic - Calbiochem Certificates of Analysis

          TitleLot Number
          368059

          References

          Reference overview
          Karahashi, H., and Amano, F. 2000. Biol. Pharm. Bull. 23, 140.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision07-July-2008 RFH
          SynonymsZ-IETD-AFC, Caspase-8 Substrate II
          DescriptionA fluorogenic substrate for the detection of granzyme B. Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore (excitation maximum: ~400 nm; emission maximum: ~505 nm).
          FormWhite lyophilized solid
          Chemical formulaC₃₇H₄₂F₃N₅O₁₃
          Peptide SequenceZ-Ile-Glu-Thr-Asp-AFC
          Purity≥97% by HPLC
          SolubilityDMSO (1 mg/ml)
          Storage -20°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Toxicity Standard Handling
          ReferencesKarahashi, H., and Amano, F. 2000. Biol. Pharm. Bull. 23, 140.

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          Categories

          Life Science Research > Inhibitors and Biochemicals