505823 Galectin-1 Antagonist, DB21 - Calbiochem

505823
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Overview

Replacement Information

Key Specifications Table

Empirical Formula
C₈₃H₁₃₂N₁₈O₁₇

Pricing & Availability

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      Glass bottle 2 mg
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      Description
      OverviewA dibenzofuran conjugated peptidomimetic (13-mer) that acts as an allosteric inhibitor of galectin-1 binding to cell surface glycans (IC50 = 3 µM). Shown to reduce the proliferation of endothelial cells and reduce vessel density in murine tumor models.
      Catalogue Number505823
      Brand Family Calbiochem®
      SynonymsSVQNvaKL-[DBF]-IIVKLNA
      References
      ReferencesDings, R.P., et al, 2013, J. Pharm. Exp. Ther. 344, 589.
      Product Information
      FormWhite powder
      Hill FormulaC₈₃H₁₃₂N₁₈O₁₇
      Chemical formulaC₈₃H₁₃₂N₁₈O₁₇
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetGalectin-1
      Primary Target IC<sub>50</sub>
      Purity≥98% by HPLC
      Physicochemical Information
      Peptide SequenceSVQMKNva-[DBF]-IIVKLNA
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Galectin-1 Antagonist, DB21 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Dings, R.P., et al, 2013, J. Pharm. Exp. Ther. 344, 589.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision06-December-2013 JSW
      SynonymsSVQNvaKL-[DBF]-IIVKLNA
      DescriptionA dibenzofuran conjugated peptidomimetic (13-mer) that acts as an allosteric inhibitor of galectin-1 binding to cell surface glycans (IC50 = 3 µM). Shown to reduce the proliferation of endothelial cells and reduce vessel density in murine tumor models.
      FormWhite powder
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₈₃H₁₃₂N₁₈O₁₇
      Peptide SequenceSVQMKNva-[DBF]-IIVKLNA
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (10 mg/ml)
      Storage -20°C
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesDings, R.P., et al, 2013, J. Pharm. Exp. Ther. 344, 589.