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344215 Formononetin - CAS 485-72-3 - Calbiochem

Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
485-72-3C₁₆H₁₂O₄

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344215-5MG
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      Plastic ampoule 5 mg
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      Description
      OverviewA phytoestrogenic isoflavone found in soy-based foods. Displays potent antioxidant properties and acts as a selective inhibitor of the γ-isoform of alcohol dehydrogenase. Shown to interact with human estrogen receptors with low potency. Induces mammary gland proliferation in mice.
      Catalogue Number344215
      Brand Family Calbiochem®
      Synonyms7-Hydroxy-3-(4ʹ-methoxyphenyl)-4H-benzopyran-4-one
      References
      ReferencesPool-Zobel, B.L., et al. 2000. Carcinogenesis 21, 1247.
      Toda, S., and Shirataki, Y. 1999. Phytother. Res. 13, 163.
      Ruiz-Larrea, M.B., et al. 1997. Free Radic. Res. 26, 63.
      Keung, W.M. 1995. Biochem. Biophys. Res. Commun. 215, 1137.
      Wang, W., et al. 1995. Nutr. Cancer 23, 131.
      Miksicek, R.J. 1994. J. Steroid Biochem. Mol. Biol. 49, 153.
      Product Information
      CAS number485-72-3
      ATP CompetitiveN
      FormWhite to off-white solid
      Hill FormulaC₁₆H₁₂O₄
      Chemical formulaC₁₆H₁₂O₄
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetSelective inhibitor of the γ-isoform of alcohol dehydrogenase
      Purity≥90% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Do not re-freeze any thawed aliquots.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Formononetin - CAS 485-72-3 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Formononetin - CAS 485-72-3 - Calbiochem Certificates of Analysis

      TitleLot Number
      344215

      References

      Reference overview
      Pool-Zobel, B.L., et al. 2000. Carcinogenesis 21, 1247.
      Toda, S., and Shirataki, Y. 1999. Phytother. Res. 13, 163.
      Ruiz-Larrea, M.B., et al. 1997. Free Radic. Res. 26, 63.
      Keung, W.M. 1995. Biochem. Biophys. Res. Commun. 215, 1137.
      Wang, W., et al. 1995. Nutr. Cancer 23, 131.
      Miksicek, R.J. 1994. J. Steroid Biochem. Mol. Biol. 49, 153.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision31-May-2018 JSW
      Synonyms7-Hydroxy-3-(4ʹ-methoxyphenyl)-4H-benzopyran-4-one
      DescriptionA non-steroidal phytoestrogenic isoflavone found in soy-based food products. Has been shown to interact with human estrogen receptor with relatively low potency. Induces mammary gland proliferation in mice. Inhibits lecithin peroxidation induced by hydroxyl radicals. Also acts as a selective inhibitor of γ-isoform of alcohol dehydrogenase.
      FormWhite to off-white solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number485-72-3
      Chemical formulaC₁₆H₁₂O₄
      Structure formulaStructure formula
      Purity≥90% by HPLC
      SolubilityDMSO (200 mg/ml) or Methanol (2 mg/ml)
      Storage -20°C
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Do not re-freeze any thawed aliquots.
      Toxicity Irritant
      Merck USA index14, 4244
      ReferencesPool-Zobel, B.L., et al. 2000. Carcinogenesis 21, 1247.
      Toda, S., and Shirataki, Y. 1999. Phytother. Res. 13, 163.
      Ruiz-Larrea, M.B., et al. 1997. Free Radic. Res. 26, 63.
      Keung, W.M. 1995. Biochem. Biophys. Res. Commun. 215, 1137.
      Wang, W., et al. 1995. Nutr. Cancer 23, 131.
      Miksicek, R.J. 1994. J. Steroid Biochem. Mol. Biol. 49, 153.