341576 Fibrinogen, Human Plasma

341576
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341576-100MG
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      341576-1GM
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          Description
          OverviewNative fibrinogen from human plasma. A plasma glycoprotein, essential for clotting of blood, synthesized and secreted by hepatic parenchymal cells. Contains ≥ 90% clottable proteins.
          Do not disturb until the fibrinogen is completely solubilized.
          Catalogue Number341576
          Brand Family Calbiochem®
          SynonymsCoagulation Factor I
          References
          Product Information
          CAS number9001-32-5
          FormLyophilized
          FormulationLyophilized from 20 mM sodium citrate-HCl, pH 7.4.
          Quality LevelMQ100
          Applications
          ApplicationFibrinogen, CAS 9001-32-5 , is a soluble plasma glycoprotein that is synthesized in the hepatic parenchymal cells. Contains >90% clottable protein.
          Biological Information
          Biological activityContains ≥90% clottable proteins.
          Purityhomogeneous by SDS-PAGE.
          SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 20/21/22

          Harmful by inhalation, in contact with skin and if swallowed.
          S PhraseS: 36

          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Harmful
          Storage +2°C to +8°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Do not store solutions on ice; precipitation will occur. Stock solutions are stable for up to 6 months at -70°C. Avoid freeze-thaw cycles.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Fibrinogen, Human Plasma SDS

          Title

          Safety Data Sheet (SDS) 

          Fibrinogen, Human Plasma Certificates of Analysis

          TitleLot Number
          341576
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision27-September-2007 RFH
          SynonymsCoagulation Factor I
          DescriptionNative fibrinogen from human plasma. A plasma glycoprotein, essential for clotting blood. Synthesized and secreted by hepatic parenchymal cells. Fibrinogen, also known as Coagulation Factor I, is an acute-phase plasma protein found at a concentration of about 300 mg/100 ml. Conversion of soluble fibrinogen to the insoluble clot-forming fibrin is the terminal stage of blood clotting. Clinically, fibrinogen is found at elevated levels during pregnancy, after surgical trauma, or in cases of myocardial infarction, and is decreased in cases of liver cirrhosis and serum hepatitis.
          FormLyophilized
          FormulationLyophilized from 20 mM sodium citrate-HCl, pH 7.4.
          SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
          CAS number9001-32-5
          Purityhomogeneous by SDS-PAGE.
          Biological activityContains ≥90% clottable proteins.
          SolubilitySterile distilled H₂O. Protein must be thawed in a 37°C water bath. Solutions used to reconstitute fibrinogen should first be brought to 37°C. Once at 37°C, the solution can be added to the fibrinogen and this mixture should remain at 37°C until the fibrinogen is completely solubilized. If the vial is disturbed before the fibrinogen is completely dissolved, the fibrinogen will precipitate. Please see vial label for lot-specific reconstitution volume.
          Storage +2°C to +8°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Do not store solutions on ice; precipitation will occur. Stock solutions are stable for up to 6 months at -70°C. Avoid freeze-thaw cycles.
          Toxicity Harmful
          Merck USA index14, 4071