374096 Sigma-AldrichEosinophil Peroxidase, Human
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Eosinophil Peroxidase, Human MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: EPO
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Overview
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Pricing & Availability
Catalog Number | Availability | Packaging | Qty/Pack | Price | Quantity | |
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374096-50UG |
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Plastic ampoule | 50 μg |
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Description | |
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Overview | Native, human eosinophil peroxidase. Eosinophil peroxidase is a secreted hemoprotein that catalyzes oxidations of various substrates by hydrogen peroxide. Together with other leukocyte-derived enzymes, such as Myeloperoxidase (Cat. No. 475911), EPO plays an important role in the pathogenesis of asthma by mediating oxidative events that lead to the production of ROS (reactive oxygen species) and RNS (reactive nitrogen species). |
Catalogue Number | 374096 |
Brand Family | Calbiochem® |
Synonyms | EPO |
Product Information | |
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CAS number | 9003-99-0 |
Unit of Definition | One unit is defined as the amount of enzyme that will cause an increase in absorbance of 1 at 470 nm per min at pH 7.0 and 25°C, calculated from the initial linear rate of reaction using guaiacol as substrate. |
EC number | 1.11.1.7 |
Form | Lyophilized |
Formulation | Lyophilized from 5 mM phosphate buffer, pH 7.0. |
Quality Level | MQ100 |
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Documentation
Eosinophil Peroxidase, Human SDS
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Eosinophil Peroxidase, Human Certificates of Analysis
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374096 |
References
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Andreadis., et al. 2003. Free Radic. Biol. Med. 35, 213. Borelli, V., et al. 2003. Infect. Immun. 71, 605. Erpenbeck, V.J., et al. 2003. Clin. Exp. Allergy 33, 331. McElhinney, B., et al. 2003. J. Leukoc. Biol. 74, 897. Aldridge, R.E., et al. 2002. Free Radic. Biol. Med. 33, 847. Kettle, A.J., and Winterbourn, C.C. 1988. Biochim. Biophys. Acta 957, 185. Desser, R.K., et al. 1972. Arch. Biochem. Biophys. 148, 452. Hager, L.P., et al. 1966. J. Biol. Chem. 241, 1769. |