Durapore® 0.1 µm and 0.22 µm Optiseal® Cartridge Filters

Optiseal cartridge filters feature a revolutionary cartridge-to-housing sealing mechanism and pleated configuration, resulting in maximum sterility assurance and economical performance.



Ordering Information

Optiseal Cartridge Filters with 0.1 µm and 0.22 µm Hydrophilic Durapore Membrane Clear Sorting & Filtering
Catalog Numbericon Descriptionicon Pore Sizeicon Pack Sizeicon
LAGL04TP6Optiseal® Durapore® Cartridge Filter 0.22 µm 0.22 µm 6 Show Pricing & Availability
LAVL04TP6Optiseal® Durapore® Cartridge Filter 0.1 µm 0.1 µm 6 Show Pricing & Availability

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    The science of managing change for filters

    Technical Info

    Establishing Product Specific Bubble Point Specifications For Sterilizing-Grade Filters


    Can Durapore 0.22 micron cartridges be used in the reverse direction?Durapore filters are bidirectionally supported. If the filter is inadvertently used in the reverse direction, a post-use integrity test will identify whether or not the filter cartridge was integral during processing. The specification for theis filter is > 50.0 psi for a water bubble point test and < 13.3 ml/minute per 10"element for a diffusion test. If the filter passes this test, no damage occured during use.

    Please note that the maximum allowable pressure specification is different in the reverse direction - 50 psid vs. 80 psid in the forward direction.
    What are the most common causes of filter clogging (air bubbles, particulates, surface tension, inappropriate filter size etc.)?Trapped bubbles, particulates and improper sizing are all common causes of fitration issues. True filter clogging is caused by particulates. Hard particles will form a cake on the filter surface. This will generally slow the filtration but not necessarily block filtration becuase fluid can flow through the layer of hard particles and then through the filter.

    Deformable particles can compress across the filter pores, forming impermeable barriers to filtration. This type of problem is common with solutions containing proteins or lipids.

    User Guides

    Hydrophilic Durapore® Cartridges and Capsules User Guide

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    Biopharmaceutical Manufacturing > Downstream Processing > Sterile Filtration > Sterile Liquid > Durapore