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DPP4 DPP IV Inhibitor

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DPP4
1 mL  
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      Overview

      Replacement Information
      Description
      Catalogue NumberDPP4
      DescriptionDPP IV Inhibitor
      References
      Product Information
      Quality LevelMQ100
      Applications
      Biological Information
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides.
      Gene Symbol
      • DPP4
      • CD26
      • ADCP2
      • DPPIV
      • ADABP
      • TP103
      • EC 3.4.14.5 [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form)
      • Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)].
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P27487 # Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline. Plays a role in T-cell activation.
      SIZE: 766 amino acids; 88279 Da
      SUBUNIT: Homodimer or heterodimer with Seprase (FAP).
      SUBCELLULAR LOCATION: Dipeptidyl peptidase 4 soluble form: Secreted. & Cell membrane; Single-pass type II membrane protein.
      TISSUE SPECIFICITY: Expressed in the poorly differentiated crypt cells of the small intestine as well as in the mature villous cells. Expressed at very low levels in the colon.
      PTM: The soluble form (SDPP) derives from the membrane form (MDPP) by proteolytic processing.
      SIMILARITY: SwissProt: P27487 ## Belongs to the peptidase S9B family. DPPIV subfamily.
      Physicochemical Information
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      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Storage ConditionsUpon arrival, store at 4°C. For long-term of more than 2 weeks, store at –20°C.
      Packaging Information
      Material Size1 mL
      Transport Information
      Supplemental Information
      Specifications