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500111 Cocarboxylase tetrahydrate

(thiamine diphosphoric acid ester tetrahydrate) EMPROVE® API

Cocarboxylase tetrahydrate MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 68684-55-9 EC Number: 205-230-7 Molar Mass: 496.37 g/mol Hill Formula: C₁₂H₁₈N₄O₇P₂S * 4 H₂O
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500111
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Key Specifications Table

CAS #EC NumberHill FormulaMolar Mass
68684-55-9205-230-7C₁₂H₁₈N₄O₇P₂S * 4 H₂O496.37 g/mol

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      5001115000
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          Description
          Catalogue Number500111
          References
          Product Information
          CAS number68684-55-9
          EC number205-230-7
          Hill FormulaC₁₂H₁₈N₄O₇P₂S * 4 H₂O
          Molar Mass496.37 g/mol
          HS Code2936 22 00
          Structure formula ImageStructure formula Image
          Quality LevelMQ600
          Applications
          Biological Information
          Physicochemical Information
          pH value2.4 - 3.2 (100 g/l, H₂O, 20 °C)
          Bulk density450 kg/m3
          Solubility55 g/l
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Storage class10 - 13 Other liquids and solids
          WGKWGK 1 slightly hazardous to water
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          StorageStore at +2°C to +25°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Assay (HPLC, calc.on anhydrous substance)96.0 - 101.0 %
          Identity (IR-spectrum)passes test
          pH-value (10 %; water)2.4 - 3.2
          Chloride (Cl) (Ion Chromatography)≤ 0.025 %
          Free phosphate (PO₄)≤ 1.0 %
          Al (Aluminium) (#)≤ 0.0010 %
          As (Arsenic)≤ 0.0003 %
          Ni (Nickel) (#)≤ 0.0002 %
          Thiamine phosphoric acid ester (HPLC)≤ 1.5 %
          Thiamin (HPLC)≤ 0.1 %
          Dithiamine Triphosphate (HPLC)≤ 0.25 %
          Impurity A (HPLC)≤ 0.1
          Impurity B (HPLC)≤ 0.1
          Related substances (HPLC)≤ 1.5 %
          Water14.0 - 16.5 %
          Endotoxins< 12
          Residual Solvents of class 3 ((2-Propanol) according to ICH Q3C)≤ 0.2 %
          Other residual solvents (according to ICH Q3C)excluded by manufacturing process
          Microbiological testpasses test
          Colony count (aerobic bacteria (TAMC))≤ 1000 CFU/g
          Colony count (Yeasts and moulds (TYMC))≤ 100 CFU/g
          E.colipasses test
          Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities).
          Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (#).
          Residues of metal or metal reagents acc. to EMEA/CHMP/SWP/ 4446/2000 are not likely to be present.
          Global Trade Item Number
          Catalog Number GTIN
          5001110100 04027269394547
          5001115000 04022536255910

          Documentation

          Emprove® API Advanced Information Package

          Title

          Emprove® API Information Package

          Title

          Cocarboxylase tetrahydrate SDS

          Title

          Safety Data Sheet (SDS) 

          Cocarboxylase tetrahydrate Certificates of Analysis

          Product Number PackagingSpecificationLot Number
          5001110100 Plastic bottlePDF Specification Document
          5001115000 Plastic bottlePDF Specification Document

          Certificates

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          Brochure

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