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233156 Cleland’s Reagent, Molecular Biology Grade - CAS 3483-12-3 - Calbiochem

Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
3483-12-3C₄H₁₀O₂S₂

Pricing & Availability

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233156-10GM
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      233156-1GM
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          Description
          OverviewA protective agent for SH groups.
          Catalogue Number233156
          Brand Family Calbiochem®
          Synonyms1,4-Dithiothreitol, DTT
          References
          Product Information
          CAS number3483-12-3
          FormWhite solid to powder
          Hill FormulaC₄H₁₀O₂S₂
          Chemical formulaC₄H₁₀O₂S₂
          Quality LevelMQ100
          Applications
          Biological Information
          Purity≥99% by titration
          Physicochemical Information
          ContaminantsDNases, proteases, RNases: none detected. Absorbance (100 mM, 1 cm, 260 nm): ≤0.500; (100 mM, 1 cm, 280 nm): ≤0.100
          Heavy metals≤0.001%
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSEK1610000
          Safety Information
          R PhraseR: 22-36/38

          Harmful if swallowed.
          Irritating to eyes and skin.
          S PhraseS: 26-36

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Harmful
          Storage +2°C to +8°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Catalog Number GTIN
          233156-10GM 04055977217759
          233156-1GM 07790788054281

          Documentation

          Cleland’s Reagent, Molecular Biology Grade - CAS 3483-12-3 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          Cleland’s Reagent, Molecular Biology Grade - CAS 3483-12-3 - Calbiochem Certificates of Analysis

          TitleLot Number
          233156
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision14-November-2017 JSW
          Synonyms1,4-Dithiothreitol, DTT
          DescriptionWater-soluble protective reagent for sulfhydryl groups [absorbance (100 mM): ≤0.5 at 260 nm; ≤0.1 at 280 nm]. It is capable of maintaining monothiols completely in the reduced state and of reducing disulfides quantitatively. Since it readily permeates cell membranes, it can protect protein sulfhydryls and restore enzyme activity lost by oxidation.
          FormWhite solid to powder
          Intert gas (Yes/No) Packaged under inert gas
          CAS number3483-12-3
          RTECSEK1610000
          Chemical formulaC₄H₁₀O₂S₂
          Purity≥99% by titration
          ContaminantsDNases, proteases, RNases: none detected. Absorbance (100 mM, 1 cm, 260 nm): ≤0.500; (100 mM, 1 cm, 280 nm): ≤0.100
          SolubilityH₂O (15 mg/ml)
          Storage +2°C to +8°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Harmful
          Merck USA index14, 3376