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220551 Chloramphenicol - CAS 56-75-7 - Calbiochem

Overview

Replacement Information

Key Specifications Table

Empirical FormulaCAS #
C₁₁H₁₂Cl₂N₂O₅ 56-75-7

Pricing & Availability

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220551-100GM
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      Glass bottle 100 gm
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      220551-25GM
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          220551-500GM
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              Description
              OverviewSynthetic bacteriostatic antibiotic that inhibits the translation of RNA by blocking the peptidyltransferase reaction on ribosomes.
              Catalogue Number220551
              Brand Family Calbiochem®
              References
              ReferencesLech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1, (Ausubel, F.M., et al., Eds.) John Wiley & Sons, New York.
              Lu, J., and Jiang, C. 1993. Biochem. Biophys. Res. Commun. 196, 12.
              Saltarelli, M.J., et al. 1993. Virol. 197, 35.
              Holt, J.T. 1992. Ann. N.Y. Acad. Sci. 660, 88.
              Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, NY, p. 1.6, A.6.
              Product Information
              CAS number56-75-7
              FormGrayish to off-white crystalline powder
              Hill FormulaC₁₁H₁₂Cl₂N₂O₅
              Chemical formulaC₁₁H₁₂Cl₂N₂O₅
              Structure formula ImageStructure formula Image
              Quality LevelMQ100
              Applications
              Biological Information
              Biological activityPotency: ≥970 µg/mg
              Primary Targettrasnslation of RNA
              Purity≥97% by Assay
              Physicochemical Information
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              RTECSAB6825000
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Ambient Temperature Only
              Storage +15°C to +30°C
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications

              Documentation

              Chloramphenicol - CAS 56-75-7 - Calbiochem SDS

              Title

              Safety Data Sheet (SDS) 

              Chloramphenicol - CAS 56-75-7 - Calbiochem Certificates of Analysis

              TitleLot Number
              220551

              References

              Reference overview
              Lech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1, (Ausubel, F.M., et al., Eds.) John Wiley & Sons, New York.
              Lu, J., and Jiang, C. 1993. Biochem. Biophys. Res. Commun. 196, 12.
              Saltarelli, M.J., et al. 1993. Virol. 197, 35.
              Holt, J.T. 1992. Ann. N.Y. Acad. Sci. 660, 88.
              Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, NY, p. 1.6, A.6.

              Brochure

              Title
              Antibiotics Profiler
              Overnight Express Autoinduction Systems

              Technical Info

              Title
              EMD Millipore Regulated Product Information
              Data Sheet

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision07-January-2014 JSW
              DescriptionSynthetic bacteriostatic antibiotic that inhibits the translation of RNA to protein by binding to the 50S ribosomal subunit, blocking the peptidyl transferase reaction. Chloramphenicol resistance is encoded by the resistance gene cat, whose product, chloramphenicol acetyltransferase, inactivates the antibiotic via acetylation. Typically used at 30-50 µg/ml for selection of chloramphenicol-resistant Escherichia coli.
              FormGrayish to off-white crystalline powder
              CAS number56-75-7
              RTECSAB6825000
              Chemical formulaC₁₁H₁₂Cl₂N₂O₅
              Structure formulaStructure formula
              Purity≥97% by Assay
              Biological activityPotency: ≥970 µg/mg
              SolubilityEthanol, Methanol (35 mg/ml), or H₂O (2.5 mg/ml)
              Storage +15°C to +30°C
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.
              Merck USA index14 2077
              ReferencesLech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1, (Ausubel, F.M., et al., Eds.) John Wiley & Sons, New York.
              Lu, J., and Jiang, C. 1993. Biochem. Biophys. Res. Commun. 196, 12.
              Saltarelli, M.J., et al. 1993. Virol. 197, 35.
              Holt, J.T. 1992. Ann. N.Y. Acad. Sci. 660, 88.
              Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, NY, p. 1.6, A.6.

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              Categories

              Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Other Inhibitors of Biological Interest > Protein Synthesis Inhibitors
              Life Science Research > Inhibitors and Biochemicals > Biochemicals > Antibiotics > Antimicrobial Agents
              Life Science Research > Cell Culture and Systems > Antibiotics & Selection Agents